Asli Bahadirli Talbott
Asli holds a BSc in Biomedical Sciences from the University of Istanbul and an MSc in Biomedical Sciences degree from Hacettepe University. She is currently working as a research specialist at the Johns Hopkins University.
CA-125 may be useful for the diagnosis of deep infiltrating endometriosis
Marco Aurélio Oliveira et al. conducted a prospective study at outpatient gynecology clinic and Endometriosis Treatment Center in Pedro Ernesto University Hospital (Rio de Janeiro State University) between January 2012 and January 2016 with two groups of patients: deep infiltrating endometriosis (DIE) case group and tubal ligation control group. The performance of CA-125 measurement was evaluated in the menstrual and mid-cycle phases of the cycle, and the difference between the two the for an early diagnosis of DIE. It is a…
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Inhibition of key neurotransmitter could reduce endometriosis-related pain
This study published in the scientific journalMolecular MedicineReports[link] by Lian et al. from Shanghai, China, aims to explore the relationship between transient receptor potential vanilloid type 1 (TRPV1) and endometriosis-associated pain. Pain is the most common symptom for women with endometriosis. TRPV1 is a protein found in the dorsal root ganglion area of the spinal cord. It plays a key role in activating pain sensitization pathways and pro-inflammation proteins like calcitonin gene-related peptide (CPRG) and substance P (SP). The dorsal…
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Body size, adult height and endometriosis
Endometriosis is associated with lean body size during childhood, adolescence, and adulthood; tall total adult height; and tall sitting height, found a study published in the scientific journal, Human Reproduction. This study aimed to investigate the relationships between body size across the life course, adult height, components of adult height (sitting height and leg length) and endometriosis risk in a study of French women containing more than 60.000 women among which a total of 2416 surgically confirmed endometriosis cases were present. They…
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A potential indicator of invasive endometriosis.
Furuya & Masuda et al., in their recent article that will be published in Acta Obstet Gynecol Scand, report that the protein encoded by ZEB1 gene (Zinc finger E-box-Binding homeobox) is a potential indicator of invasive endometriosis. ZEB1 is a transcription factor that has been implicated in the malignant progression of tumors, such lung cancers. Endometriotic implants that penetrate the retroperitoneal space more than 5 mm are defined as "deeply infiltrating endometriosis" and strongly associated with severe chronic pelvic pain, dyspareunia (painful sexual intercourse) and menstrual cramps. The…
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How Resveratrol is effective in endometriosis?
In their review paper, Mohammadi and Arablou recommend using Resveratrol, a plant-derived compound, for the treatment of endometriosis. Resveratrol is abundant in nature and can be found in many different plant species, fungi, berries, peanuts, legumes, and grasses; however, grapes and red wines are considered the primary source of Resveratrol. Experiments done in rats and humans show that Resveratrol is absorbed by the intestines and is later metabolized in the liver. Finally, renal excretion also allows Resveratrol to exit the…
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Can a cure be developed for endometriosis?
The Lancet correspondence highlights that regardless of the importance of endometriosis; its full socioeconomic impact is underestimated and endometriosis research is considerably underfunded. The Endometriosis Priority Setting Partnership (PSP) which includes women with endometriosis, their supporters, health-care practitioners, endometriosis researchers, and representatives from organizations related to endometriosis, aims to identify the key questions about endometriosis that were most important to both women with endometriosis and healthcare practitioners involved in their care. In the first online survey, 1225 respondents from the UK and Ireland participated. Participants submitted…
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Diet & Endometriosis
Diet and the risk of developing endometriosis Current studies examining the modifiable risk factors for prevention of endometriosis are pointing to the development of effective dietary restrictions. Thus understanding the role of nutrition in endometriosis has become critical. In a recently published review paper in Ginekologia Polska https://journals.viamedica.pl/ginekologia_polska/article/view/47748, Jurkiewicz-Przondziono et al. at the Medical University of Silesia, Poland have summarized their literature findings. The team listed seven food groups and their impact on developing endometriosis.Jurkiewicz-Przondziono et al. suggested that there…
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