By Eylül GÜNAnti-IL-8 antibody ameliorates inflammation and fibrosis: A promising treatment for endometriosis
By Eylül GÜN
Endometriosis is a condition associated with chronic inflammation and fibrosis, and there are limitations and side effects with current treatments such as hormonal therapy and surgery. Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP1) are inflammatory cytokines that play a crucial…
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By Nasuhi Engin AydinAntiinflammatory lactoferrin molecule and antibody levels in endometriosis patients
By Nasuhi Engin Aydin
A Japanese clinical research team led by Dr. Kaya Mori-Yamanaka from Shiga University of Medical Science Hospital, Otsu, Shiga, Japan, published their pioneering study on the role of serum lactoferrin and anti-lactoferrin antibody levels in endometriosis in a recent issue of…
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An important matter to revise: Immune system changes in endometriosis
By Eylül GÜN
Endometriosis is a multifactorial disease with unclear and obscure pathogenetic mechanisms. In their review, Chopyak et al. revised the immunopathogenic pathways that are proven and/or thought to be responsible for disease development and progression. The article was published in the…
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Prolactin receptor antibodies: A novel treatment proposal for endometriosis
By Eylül GÜN
Prolactin, a hormone that also acts as a proinflammatory cytokine through its receptor PRLR has been shown to be involved in endometriosis pathogenesis. Previous studies reported that women suffering from endometriosis had elevated prolactin levels. Also, in experimental studies done…
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By Özge ÖzkayaAntinuclear Antibody May Be Linked to Milder Disease in Endometriosis
By Özge Özkaya
The prevalence of positive antinuclear antibody was 21.2% in women with endometriosis compared to 5.4% in controls, according to a new study published in the journal Human Immunology. Antinuclear antibodies are autoantibodies that bind to the content of the cell…
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By Yu YuThe link between autoimmunity and endometriosis
By Yu Yu
A popular model to explain the etiology of endometriosis is Sampson’s theory of retrograde menstruation. In this model, the viable endometrial tissue is spread and attached to the peritoneal cavity through the fallopian tubes during menstruation, resulting in an inflammatory…
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