Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.
Dr. Matsuzaki et al. (2018) published a paper entitled ‘In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis’ showing that the efficacy of MK2206, an Akt inhibitor, in combination with chloroquine for inducing autophagy in…
Key Points Lay SummaryThe effects of MK2206 and chloroquine combination therapy on endometriosis.
Endometriosis affects approximately 10% of women of reproductive age. A high recurrence rate after medical treatment with or without surgery is a significant clinical problem for patients with endometriosis. Establishment of a complete cure for patients with endometriosis awaits new…
Key Points Lay Summary