By Özge ÖzkayaStudy Identifies Potential New Theraputic Target in Endometriosis
By Özge Özkaya
Lactate could drive the progression of endometriosis by upregulating the expression of a gene called HMGB1, according to a new study published in the Journal of Biomedical Research. This finding identifies novel targets for the prevention and treatment of endometriosis.…
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By Irem OnurA nonhormonal treatment of endometriosis: Dichloroacetate
By Irem Onur
In women with endometriosis, peritoneal mesothelial cells show higher glycolysis, lower mitochondrial respiration, decreased enzymatic activity of pyruvate dehydrogenase and increased production of lactate compared to women without the disease. Transforming growth factorβ1 and lactate are elevated in the peritoneal…
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