Immune Dynamics in Adolescent Peritoneal Endometriosis
In a study published in the Cells, Khashchenko et. al investigated the potential role of immune cell imbalances in adolescent peritoneal endometriosis, and their potential impact on disease progression and response to progestogen therapy. This study provides new insights into how immune imbalances in adolescents with…
Key Points Lay SummaryInterleukin-35 expression in B lymphocytes: A new potential biomarker?
Regulatory T-cells (Tregs) and B-cells (Bregs) play a crucial role in establishing tolerance to self-antigens and suppressing immune activity. Therefore, in endometriosis, they are requisite for the endometriotic cells to survive outside the uterus. They suppress immune activity by producing…
Key Points Lay SummaryCD4, CD8 T lymphocytes gain importance in endometriosis
Immune dysregulation is important in the development of endometriosis where the role of various lymphocyte subpopulations has been investigated up till now. Caihua Li and associates from Anhui Medical University, China, made a unique observation regarding CD4 and CD8 T…
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