By Nasuhi Engin AydinChronic stress may be involved both in the pathogenesis and progression of endometriosis
By Nasuhi Engin Aydin
Chong Lu and associates from Shangai, China have published their novel research on chronic stress and endometriosis in a recent issue of International Journal of Molecular Sciences. During the natural course of endometriosis many patients are under chronic stress, which…
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By Dr. Youngran ParkmiR-92a and progesterone resistance in endometriosis
By Dr. Youngran Park
Endometriosis is an estrogen-dependent disorder. This incidence of this disease is 35% to 50% among those who suffer from chronic pelvic pain and infertility, which has a negative effect on the quality of life and on health. Recent genome-wide associations…
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Endometriosis as an epigenetically regulated disease
By Dr. Youngran Park
Endometriosis is defined as the abnormal growth of endometrial tissue outside of the uterus. It affects about 10% of reproductive age women resulting in severe pain and infertility. Among various theories of endometriosis pathogenesis, not a single one has successfully…
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By Selma OransayMTA1 as a predictor for the progression of endometriosis.
By Selma Oransay
Jing Zhang et al. from the Department of Obstetrics and Gynecology, Affiliated Haikou Hospital, Xiangya Medical College of Central South University, Hainan, China, published their article in the open access medical journal "Medicine". Their aim was to evaluate the relationship between…
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By Kasthuri NairPolymorphism of IL12B May Help Solve Endometriosis
By Kasthuri Nair
Zhao et al. recently published a paper titled “A functional promoter polymorphism in interleukin 12B gene is associated with an increased risk of ovarian endometriosis” in Gene. The research group from Hebei Medical University wanted to explore the potential roles…
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HOXA10: A Culprit in Endometriosis Disease Progression
By Kasthuri Nair
Zheng et al., a group of authors from the Aerospace Center Hospital in Bejing and from the First Affiliated Hospital of Wenzhou Medical University in Wenzhou, recently published a paper in Reproductive Sciences entitled “Decreased Expression of HOXA10 May Activate the…
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High-Mobility Group Box 1 Expression Could Lead to Disease Progression
By Kasthuri Nair
Endometriosis can often be characterized by the aberrant ectopic growth of endometriotic stromal cells (ESCs); however, research has yet to elucidate the mechanism driving this growth. The authors of this study, namely Shimizu et al., believe that the high-mobility group…
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