Study May Explain How Tubal Endometriosis Causes Infertility
Tubal endometriosis damages the epithelial ultrastructure of the fallopian tubes or the tubes connecting the ovaries to the uterus along which an egg travels each month ready to be fertilized by a sperm cell. This could help explain why tubal…
Key Points Lay SummaryA new potential biomarker proposal from leukorrhea of endometriosis patients
Endometriosis is typically diagnosed through laparoscopic surgery, which can be invasive and discourages some patients from participating. Therefore, there is a need for a non-invasive diagnostic method. Exosomes, small vesicles containing biological information, can be found in almost every type…
Key Points Lay SummaryResearch Identifies New Genes That Could Be Targeted to Treat Endometriosis
Researchers identified three new genes that could help understand the invasiveness of endometriosis. They also identified one new gene that could be related to the recurrence of the disease. These genes may potentially be new therapeutic targets for endometriosis. In…
Key Points Lay SummaryRole of miR-141 in endometriosis
MicroRNAs (miRNAs) are short (18–24 nucleotides) endogenous non-coding RNAs that regulate a broad range of signaling pathways. They bind to specific sequences resulting in mRNA degradation and protein inhibition. Deregulation of miRNAs is associated with the development of many disease…
Key Points Lay SummaryThe reason for lower BMI and less body fat in women with endometriosis.
Zolbin et al. from the Department of Obstetrics and Gynecology of Yale School of Medicine, New Haven, USA, recently published the results of their prospective controlled research on adipocyte alterations in endometriosis, in the journal "Reproductive Biology and Endocrinology". Endometriosis can…
Key Points Lay SummaryImmunologic Disorder in the Progression of Endometriosis
Endometriosis becomes increasingly a health-social problem. However, definite diagnostic biomarkers and more effective treatments for endometriosis are still missing to this day. Many researchers focus on the peritoneal microenvironment of patients with endometriosis, especially the immunological microenvironment. Recently, Jørgensen et…
Key Points Lay SummaryPersonalised Medicine for Endometriosis?
The lining of the uterus of women with endometriosis is different from that of women without the disease even if they have chronic pelvic pain found a study published in the scientific journal Biology of Reproduction. The difference is found…
Key Points Lay SummaryEpigenetic link between endometriosis and cancer
Although endometriosis is considered a benign condition the cellular, histologic, and molecular data strongly demonstrate that endometriosis has neoplastic characteristics. There is strong evidence that endometriosis shares striking features with malignancy like normal tissue dissemination, invasion, and organ damage, as well as new vessel formation (neoangiogenesis). In…
Key Points Lay SummarymiRNAs, Could Be a Reliable Biomarker of Endometriosis
miRNAs, small pieces of genetic material found in the blood could be used as a reliable marker to diagnose endometriosis, according to a study by U.S. researchers. They could also be used to follow the progression of the disease and…
Key Points Lay SummaryEndometriosis : A Whole Body Disease
Endometriosis is a disease that impacts multiple parts of an individual’s body. Seminars in Reproductive Medicine recently published a paper by Alderman III et al. entitled “The Systemic Effects of Endometriosis” explores the various comorbidities that can affect individuals suffering…
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