By Özge ÖzkayaNew Model Can Help Understand How Endometriosis-Associated Ovarian Cancer Develops
By Özge Özkaya
Researchers from Japan and the US developed a new mouse model in collaboration, that can be useful to better understand how endometriosis-associated ovarian cancer develops. This new model can help to assess new treatment options for both diseases. The team…
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Researchers Develop New Mouse Model of Endometriosis
By Özge Özkaya
Researchers from China developed a new mouse model to study endometriosis that could help researchers better understand the molecular mechanisms that lead to the development of endometriosis and develop potential new treatments for the disease. Even though many animal models…
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By Bahar YukselChasing gold to find endometriosis.
By Bahar Yuksel
Endometriosis is a disease that doesn’t have a proper preoperative diagnostic test. Thus, animal models to study endometriosis are vital to show the effects of drugs and the effects of the disease on the body. In the study conducted by…
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Potential New Approach to Treat Endometriosis
By Özge Özkaya
Inhibiting ribosome biogenesis could be a potential therapeutic approach for endometriosis according to a new study published in the scientific journal Biomedicines. Ribosome biogenesis plays a key role in protein homeostasis during cell growth and division. Previous research has shown…
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New Signaling Pathway Could Be Crucial in the Development of Endometriosis
By Özge Özkaya
RAMP1 signaling is crucial for growth and blood and lymphatic vessel formation in endometrial tissue, according to a new study published in the Journal of Cellular and Molecular Medicine. This suggests that blocking RAMP1 could be a new way to…
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By Selma OransayThe reason for lower BMI and less body fat in women with endometriosis.
By Selma Oransay
Zolbin et al. from the Department of Obstetrics and Gynecology of Yale School of Medicine, New Haven, USA, recently published the results of their prospective controlled research on adipocyte alterations in endometriosis, in the journal "Reproductive Biology and Endocrinology". Endometriosis can…
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Reducing the Risk of Recurrence After Endometriosis Surgery
By Özge Özkaya
The use of compounds called NF-κB inhibitors and β-blockers before and after endometriosis surgery may reduce the risk of the disease recurring, according to a study conducted in a mouse model. According to the study published in the journal Reproductive…
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Study Sheds Light on the Molecular Mechanism of Endometriosis Development
By Özge Özkaya
A protein called transforming growth factor-beta1 (TGF-B1) enhances the capacity of endometriotic cells or cells that make up the lining of the uterus to migrate, invade, and colonize other areas in the body. This is according to a study published…
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An Alternative Medical Approach to Treat Endometriosis?
By Özge Özkaya
Molecules that act on a protein called SRC-1 could constitute a new medical tool to treat endometriosis, according to a study published in the Journal of Endocrinology. SRC-1 makes certain parts of DNA more accessible therefore increasing gene expression or…
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New Target for Endometriosis Treatment?
By Özge Özkaya
NR4A1 could be a novel target for the treatment of endometriosis, according to a study published in the scientific journal Cell Physiology and Biochemistry. NR4A1 is a receptor protein involved in cell division, inflammation, and programmed cell death. The development…
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Could Gabapentin Make my Pain Go Away?
By Özge Özkaya
Gabapentin could effectively reduce endometriosis-associated pain, according to a new study published in the Journal of Pain Research. The study that was conducted in mice and endometriotic tissues from patients suggests that certain proteins present on the surface of cells…
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Restricting Calorie Intake Could Delay or Prevent Endometriosis
By Özge Özkaya
Reducing the intake of calories could stop the development of endometriosis according to research conducted in mice. This could be the case even after the lesions are established, i.e. endometriosis has started. Dietary supplements or drug candidates that mimic the…
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Potential New Target to Treat Endometriosis?
By Özge Özkaya
Special cells called myeloid-derived suppressor cells (MDSC) could be playing a role in the development of endometriosis, suggests a study published in the European Journal of Immunology. These cells could, therefore, be targeted by novel therapeutic agents to treat endometriosis. …
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Endometriosis “Changes” the Brain
By Özge Özkaya
Endometriosis changes the electrical properties of the brain as well as gene expression, according to a study by Yale researchers. These changes increase sensitivity to pain, anxiety, and depression. “While medications can be used to treat endometriosis directly, the effects…
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Plant Compound May Protect Against Endometriosis
By Özge Özkaya
Marrubiin, a compound derived from a plant in the mint family called white horehound may have protective effects against endometriosis, according to a study published in the journal Molecular Medicine Reports. Marrubiin is the main analgesic, or painkiller compound found…
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Female Sex Hormone Necessary but not Enough to Cause Endometriosis
By Özge Özkaya
Estrogen, the primary female sex hormone may be necessary but is not enough to induce endometriosis, found a study published in the Journal of Bioscience. This finding is important because it can help scientists better understand factors that cause endometriosis…
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