By Nasuhi Engin AydinPreferential expression of some membrane type matrix metalloproteinase proteins
By Nasuhi Engin Aydin
Dr. Maoga and associates from academic institutions located in Germany and Kenya have published their findings on the immunohistochemical expression of MT-MMP proteins, namely MT2-MMP (MMP15) and MT3-MMP (MMP16) in the eutopic endometrium of healthy and endometriotic patients; and also…
Key Points Lay Summary
By Eylül GÜNMatrix metalloproteinases and their role in endometriosis
By Eylül GÜN
The extracellular matrix harbors important macromolecules such as collagen and glycoproteins which are required for tissue remodeling, differentiation, and homeostasis. The main group of enzymes responsible for these properties is called matrix metalloproteinases (MMPs). It has been proven that MMPs…
Key Points Lay Summary
By Yu YuEndometriosis signaling: the role of IL-34
By Yu Yu
An increasing number of studies have suggested that the pathogenesis of endometriosis is mediated by cytokines, such as interleukin (IL)−17, which promoted the formation and progression of endometriosis by up-regulating angiogenesis and pro-inflammatory cytokines secretion. IL-34 is a newly described…
Key Points Lay Summary
By Özge ÖzkayaNew Protein for Endometriosis Diagnosis
By Özge Özkaya
A protein called TIMP3 (tissue inhibitor of metalloproteinase-3) could be used for the diagnosis and prognosis (likely course) of endometriosis. The early diagnosis of endometriosis is of paramount importance because it can help to diagnosis and thus initiate the right…
Key Points Lay Summary
By Murat OsmanA Balancing Act: How Endometriosis Invades the Body
By Murat Osman
Endometriosis is a disease defined by the presence of endometrial tissue outside of the uterine cavity. Ectopic endometrial tissues have been shown to have some features that mimic malignancy. For example, endometriosis can invade surrounding structures and attach to surfaces such…
Key Points Lay Summary
The Endometrium Itself is Genetically Different in Endometriosis Patients
By Özge Özkaya
Researchers in China identified a number of genes that are differentially expressed in the eutopic endometrium of women with endometriosis and those without. The researchers think that these genes may be involved in the development of endometriosis and that they…
Key Points Lay Summary