Endostatin-Expressing Stem Cells: A New Approach to Treating Endometriosis
Endometriosis is a chronic inflammatory condition characterized by abnormal blood vessel formation. Endostatin, a potent angiogenesis inhibitor, has shown potential in targeting the process of angiogenesis. In a study published in Stem Cells Translational Medicine, Peng and Zhang et al. explored the therapeutic…
Key Points Lay Summary
By Selma OransayAntioxidant therapy for the endometriosis pain
By Selma Oransay
Ts the protective defense mechanism of cells, hence the destruction of balance between oxidants and antioxidants in our body is called "redox imbalance". The major oxidants are reactive oxygen species (ROS) that are involved in multiple cellular processes by physiologically…
Key Points Lay Summary
By Murat OsmanLipophilic Statins inhibit growth and invasiveness of human endometrial cells
By Murat Osman
Endometriosis is a disease process whereby cells of the endometrium grow and invade structures outside of the uterus. Through recent research, it has been seen that endometriotic foci in women with endometriosis exhibit an altered phenotype that contributes to its…
Key Points Lay Summary
By Nasuhi Engin AydinGrowth Hormone-Inhibiting Hormone: Somatostatin and its receptors in endometriosis
By Nasuhi Engin Aydin
Yanhua Zhao and colleagues, led by Dr.Zhang from Hunan, China reported their recent research at Experimental and Therapeutic Medicine. Somatostatin is a natural polypeptide extensively distributed in the digestive and nervous system, exhibiting several biological effects with a restricted clinical…
Key Points Lay Summary
By Irem OnurFighting with endometriosis
By Irem Onur
Maduro M.R. reviewed three separate studies on potential new targets to successfully manage endometriosis in her recent paper titled “Novel Strategies to Fight Endometriosis” published in the journal Reproductive Sciences. In the autotransplantation rat model of Torres-Reveron et al., the…
Key Points Lay Summary
By Özge ÖzkayamiRNAs, Could Be a Reliable Biomarker of Endometriosis
By Özge Özkaya
miRNAs, small pieces of genetic material found in the blood could be used as a reliable marker to diagnose endometriosis, according to a study by U.S. researchers. They could also be used to follow the progression of the disease and…
Key Points Lay Summary
By Dr. Youngran ParkTherapeutic Roles of Statins in Gynecology and Obstetrics.
By Dr. Youngran Park
Statins are a class of drugs, which act by inhibiting the rate-limiting enzyme of cholesterol biosynthesis, which reduces lipid production. Therefore, statin has been used for the treatment of hypercholesterolemia and coronary artery disease. This study published in Reproductive Sciences performed…
Key Points Lay Summary