Taller Girls More Likely to Have Recurring Endometriosis
Adolescents who are taller and have three or more lesions are at a higher risk of endometriosis recurrence following surgery, according to a new study by Chinese researchers published in the Journal of Obstetrics and Gynaecology. They should, therefore, be…
Key Points Lay SummaryMatrix metalloproteinases and their role in endometriosis
The extracellular matrix harbors important macromolecules such as collagen and glycoproteins which are required for tissue remodeling, differentiation, and homeostasis. The main group of enzymes responsible for these properties is called matrix metalloproteinases (MMPs). It has been proven that MMPs…
Key Points Lay SummaryBone morphogenetic protein and endometriosis
Endometriosis is a chronic disease characterized by the presence of endometrial glands and stroma outside the uterus, associated with several discomforts such as pelvic pain, menstrual disorders, and infertility. Although endometriosis is categorized as a benign lesion, the ectopic endometrial…
Key Points Lay SummaryEndometriosis signaling: the role of IL-34
An increasing number of studies have suggested that the pathogenesis of endometriosis is mediated by cytokines, such as interleukin (IL)−17, which promoted the formation and progression of endometriosis by up-regulating angiogenesis and pro-inflammatory cytokines secretion. IL-34 is a newly described…
Key Points Lay SummaryNew Protein for Endometriosis Diagnosis
A protein called TIMP3 (tissue inhibitor of metalloproteinase-3) could be used for the diagnosis and prognosis (likely course) of endometriosis. The early diagnosis of endometriosis is of paramount importance because it can help to diagnosis and thus initiate the right…
Key Points Lay SummaryA Balancing Act: How Endometriosis Invades the Body
Endometriosis is a disease defined by the presence of endometrial tissue outside of the uterine cavity. Ectopic endometrial tissues have been shown to have some features that mimic malignancy. For example, endometriosis can invade surrounding structures and attach to surfaces such…
Key Points Lay SummaryThe Endometrium Itself is Genetically Different in Endometriosis Patients
Researchers in China identified a number of genes that are differentially expressed in the eutopic endometrium of women with endometriosis and those without. The researchers think that these genes may be involved in the development of endometriosis and that they…
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