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Impact of Menstrual Cycle on Cognitive Function in Midlife Women
Dementia, which affects women at more than 1.7 times the rate of men, continues to be a growing health concern, with potential links to hormonal changes. Estrogen, known for its neuroprotective effects, influences cognitive functions such as verbal memory, fluency,…
Key Points Lay SummaryImmune Cell Infiltration and Genetic Drivers in Endometriosis Development
The development of endometriosis is closely linked to immune cell infiltration, where immune cells and their secreted cytokines play a key role in driving inflammation and the formation of lesions. Studies highlight increased neutrophil infiltration in ectopic tissues, which release…
Key Points Lay SummaryImpact of appropriate surgery on endometriosis-related infertility
Endometriosis surgery by removing all visible lesions and repairing damaged tisue is important to build normal pelvic anatomy. It is still difficult to predict postoperative pregnancy rates among women with endometriosis who suffer from infertility. This retrospective study, conducted by Tahmasbi…
Key Points Lay SummaryPre-Diagnosis Hospital Utilization Patterns in Women With Endometriosis
Endometriosis is commonly associated with symptoms such as painful periods, chronic pelvic pain, and infertility. Diagnosing the condition is challenging due to symptom overlap with other gynecologic and gastrointestinal disorders, as well as the need for advanced imaging or laparoscopic…
Key Points Lay SummaryThe current management of endometriosis-related infertility.
Endometriosis is a chronic disease affecting women of reproductive age, often presenting with pelvic pain such as dyspareunia, dyschezia, and dysuria, or inertility, and significantly impacting quality of life. Management should be individualized based on symptoms, reproductive goals, age,…
Key Points Lay SummaryUnique features of endometrial cells in endometriosis
Researchers from the University of Texas, San Antonio, have published a detailed study on the properties of endometrial cell components in relation to endometriosis, entitled "Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis", in the scientific journal eLife. The…
Key Points Lay SummaryPostoperative Outcomes in Women After Sacral Plexus Deep Endometriosis Resection
Deep endometriosis refers to a severe form of endometriosis where tissue grows deeply into the pelvic and abdominal organs, including the bowel, bladder, nerves, and blood vessels. When the disease affects the sacral plexus, which is a network of nerves at the base…
Key Points Lay SummaryImpact of Nerve Preservation During Parametrectomy on Urinary Retention in Deep Endometriosis Surgery
Deep infiltrating endometriosis (DIE) is the most advanced form of the disease, characterized by lesions penetrating deeper than 5 mm. Surgical treatment requires a meticulous approach to minimize functional complications. Deep lesions involving the parametrium, uterosacral ligaments, and anterior rectal…
Key Points Lay SummaryMore Young Patients Regret Having a Hysterectomy Than Older Ones
A study published inObstetrics & Gynecology found that patients aged 30 or younger were more likely to regret their decision to undergo a hysterectomy compared to those aged 31 to 49, regardless of factors such as parity, prior sterilization, or previous…
Key Points Lay SummaryDIE Complex and Requires Interdisciplinary Approach
The vast majority of deep infiltrating endometriosis (DIE) cases are treated with minimally invasive laparoscopic surgery according to a new study published in the Journal of Clinical Medicine. Moreover, there is a high need for interdisciplinary operations. “Our results emphasize…
Key Points Lay Summary