By Nadire DuruRole of miR-141 in endometriosis
By Nadire Duru
MicroRNAs (miRNAs) are short (18–24 nucleotides) endogenous non-coding RNAs that regulate a broad range of signaling pathways. They bind to specific sequences resulting in mRNA degradation and protein inhibition. Deregulation of miRNAs is associated with the development of many disease…
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By Özge ÖzkayaEarly Developmental Gene May Play a Role in Endometriosis
By Özge Özkaya
An early developmental gene called twist may encourage the connective tissue cells of the lining of the uterus to change from being epithelial to being mesenchymal, so-called epithelial to mesenchymal transition (EMT). Mesenchymal cells play important roles in biological processes…
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By Dr. Youngran ParkLong non‐coding RNA, Epithelial mesenchymal transition, and Endometriosis
By Dr. Youngran Park
Endometriosis is an estrogen‐dependent inflammatory gynecologic disease and requires attention. However, an in‐depth understanding of the latent pathogenesis of endometriosis development and its new innovative therapeutics are urgently needed. Epithelial‐mesenchymal transition (EMT) refers to the special biological process of epithelial…
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Could the Sleep Hormone Treat Endometriosis?
By Özge Özkaya
Melatonin blocks cell proliferation, invasion, and migration in both normal and endometriotic epithelial cells, according to a study published in the scientific journal Reproductive Biology and Endocrinology. Melatonin could, therefore, be a potential treatment for endometriosis The formation and progression…
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By Nasuhi Engin AydinCommentary on major developments in the pathophysiology of endometriosis
By Nasuhi Engin Aydin
This commentary article by Dr. Warren G. Foster, from MacMaster University, Canada that appeared at Biology of Reproduction, is highly valuable for its leading role in endometriosis research. Although endometriosis is a common disease affecting up to 10% of women,…
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By Asli Bahadirli TalbottA potential indicator of invasive endometriosis.
By Asli Bahadirli Talbott
Furuya & Masuda et al., in their recent article that will be published in Acta Obstet Gynecol Scand, report that the protein encoded by ZEB1 gene (Zinc finger E-box-Binding homeobox) is a potential indicator of invasive endometriosis. ZEB1 is a transcription factor that has been implicated…
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