By Hakan Kula
In a study published in the International Journal of Molecular Sciences, Khashchenko et al. explored the association of cellular and exosomal markers of glycolysis, mitochondrial biogenesis, apoptosis, autophagy, and estrogen signaling in peritoneal endometriosis among adolescents to understand early disease-related metabolic reprogramming.
This case–control…
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By Özge Özkaya
Screening adolescents and young adult women with a questionnaire can identify clinical symptoms associated with histologically proven endometriosis, according to a new study published in the scientific journal Human Reproduction.
“Combined with imaging and clinical examination, this approach will enable…
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By Özge Özkaya
The prevalence of coded dysmenorrhoea in the records of general practitioners (GP) is significantly lower than what is suggested in community surveys, according to a new study published in the British Journal of General Practice. However, menstrual symptoms in adolescents are commonly seen…
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By Hale Goksever Celik
The main symptoms of endometriosis include dysmenorrhea, dyspareunia, and chronic pelvic pain that may result in social and developmental disturbances such as abstinence from school or work.
There is a significant diagnostic delay of endometriosis diagnosis, because symptoms may be…
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By Selma Oransay
Hormonal contraceptives are the first-line medical treatment of endometriosis. If an adolescent has chronic pelvic pain and is an "unresponder" to hormonal therapy, the likelihood of having an "endometriosis diagnosis" is higher. This sign should warn clinicians about endometriosis diagnosis…
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By Hale Goksever Celik
The quality of life in women with endometriosis is affected depending on the symptoms and signs of endometriosis such as dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Because of different clinical spectrum and diagnostic delays, there is no optimum management…
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By Selma Oransay
Many blood substances are present in peritoneal fluid due to their derivation from the transudation of blood through the peritoneal surface. Ectopic endometriotic lesions can also change the medium to contribute to the definition of the local environment of the…
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By Özge Özkaya
Younger women with endometriosis feel more period pain (dysmenorrhea) and pain during intercourse (dyspareunia) compared to older women with the disease, found a new study published in the Journal of Pediatric and Adolescent Gynecology.
Acknowledging this fact can make sure…
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By Özge Özkaya
Adolescents who are taller and have three or more lesions are at a higher risk of endometriosis recurrence following surgery, according to a new study by Chinese researchers published in the Journal of Obstetrics and Gynaecology. They should, therefore, be…
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By Selma Oransay
The occurrence of severe and frequent pelvic pain in young women is a piece of evidence that endometriosis begins and develops at an early age. Two-thirds of women with endometriosis who were diagnosed in their adulthood reported the onset of…
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By Özge Özkaya
Proteins related to angiogenesis or the formation of new blood vessels and cellular migration are enriched and more active in the blood of adolescents with endometriosis compared to healthy controls. These are the findings of a new study published in…
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By Selma Oransay
ESHRE, "European Society of Human Reproduction and Embryology" published a Guideline for the diagnosis and treatment of endometriosis in 2005 and then revised it in 2013. Based on new research and development there was a need to renew the last…
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By Nasuhi Engin Aydin
Dr. Exacoustos and colleagues from two tertiary referral university hospitals in Italy published their results on adenomyosis in adolescent patients in a recent issue of “The Journal of Minimally Invasive Gynecology”.
Adenomyosis is the presence of endometrial glands and stroma…
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By Eylül GÜN
Although the diagnosis of endometriosis is still not timely even in adults, due to its common under- or misdiagnosis in adolescents, the diagnostic delay may further cause the adolescent women to wait to seek medical treatment.
A group of researchers…
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By Selma Oransay
Recent studies showed the prevalence of endometriosis in adolescents with chronic cyclic or acyclic pelvic pain is about 60-70%. Moreover, all stages of endometriosis, including deeply infiltrating endometriosis can be found in this population.
Gubbels et al. from the Department…
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By Özge Özkaya
Clinicians should ask adolescents and young women about painful sex, not just talk about contraception and the prevention of sexually transmitted diseases. This is because painful sexual intercourse could have a negative impact on relationships and peer engagement, which is…
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By Irem Onur
An updated review conducted by the investigators at EGA Institute for Women's Health, University College London, United Kingdom, in collaboration with Birmingham Women’s and Children’s Foundation Trust of the Institute of Metabolism and Systems Research at the University of Birmingham…
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By Irem Onur
Shim J.Y. et al, from Boston, Massachusetts retrospectively searched the electronic medical records of transmasculine patients younger than 26 years old who were diagnosed with dysmenorrhea and treated at Boston Children’s Hospital, between January 1, 2000, and March 1, 2020.…
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By Timur Seckin
A recent article, led by experts from Peking Medical Union College, describes the clinical characteristics and postoperative symptoms of adolescent endometriosis.
The authors inform that their report, which is published in the "Journal of Pediatric and Adolescent Gynecology", can provide…
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By Hale Goksever Celik
Endometriosis is usually diagnosed in reproductive-aged women. However, recent literature proved that clinical symptoms of endometriosis are also seen the adolescent girls and young women.
Dysmenorrhea, the most common gynecologic complaint among this age group, can develop due to endometriosis.…
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By Yu Yu
The effective management of endometriosis requires a proper understanding of how the condition progress as women age, especially for those women with early onset of endometriosis. Several studies have tried to characterize the evolution of endometriosis. Some of the key…
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By Hale Goksever Celik
Endometriosis is an estrogen-dependent disease which is commonly diagnosed in reproductive-aged women. On the other hand, this disease can develop earlier in life due to different etiopathogenetic mechanisms. Especially adolescents who experienced neonatal uterine bleeding are under the risk for…
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By Selma Oransay
Dysmenorrhoea is typically classified as primary, or secondary due to underlying pathologies like fibroids, endometriosis, adenomyosis or uterine anomalies. Generally, long-term dysmenorrhea is present in endometriotic patient's anamnesis, but until recently, the research to clarify this connection remained retrospective.
Knox et…
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By Selma Oransay
The Korean Society of Endometriosis has scrutinized the present published literature of endometriosis in the domestic and international platform to provide new guidelines and the clinical management of the disease. The study was recently published in the journal "Obstetrics and Gynecology…
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By Irem Onur
Dr. Mama S. T. from Cooper University Hospital, Camden, New Jersey, USA, recently has published his review on advances in the management of endometriosis in the adolescent in the journal “Current Opinion Obstetrics and Gynecology”.
In adolescence, there is a…
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By Deniz Kocas
González-Echevarría et al. report in J Psychosom Obstet Gynaecol. that symptoms caused by endometriosis have been found to be associated with negative quality of life (QoL) in women with endometriosis and the type of coping strategies adopted by patients have been shown…
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By Özge Özkaya
Most women with endometriosis who have been treated with Lupron plus add back as adolescents felt the treatment was effective in reducing the pain caused by the condition, according to a study published in the Journal of Pediatric & Adolescent…
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By Kasthuri Nair
Miller et al. recently published an article titled “The prevalence of migraines in adolescents with endometriosis” in Fertility and Sterility. The main purpose of the study was to determine if adolescents with endometriosis experience more migraines than those without endometriosis.…
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By Murat Osman
Early onset endometriosis (EOE) is characterized by endometriosis that begins around menarche or early adolescence. Recent evidence suggests that this form of endometriosis may have a different pathogenic origin than that of adult-onset endometriosis. This opinion article suggests that early…
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By Özge Özkaya
Symptoms of endometriosis seem to be the same between women surgically diagnosed during adolescence and those diagnosed as adults, according to a study published in the American Journal of Obstetrics and Gynecology. For both age groups, pelvic pain was severe,…
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