By Selma OransayEndometriosis in Adolescents: Diagnosis, Treatment, and Challenges
By Selma Oransay
Endometriosis is a condition that affects not only adult women but also adolescents, regardless of their race, ethnicity, or socioeconomic status. It can cause significant pain, including dysmenorrhea and pelvic pain. Research has shown that up to 20% of transgender…
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Early use of hormonal contraceptives and the probability of endometriosis diagnosis later in life
By Selma Oransay
Hormonal contraceptives are the first-line medical treatment of endometriosis. If an adolescent has chronic pelvic pain and is an "unresponder" to hormonal therapy, the likelihood of having an "endometriosis diagnosis" is higher. This sign should warn clinicians about endometriosis diagnosis…
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Peritoneal fluid in young women with endometriosis
By Selma Oransay
Many blood substances are present in peritoneal fluid due to their derivation from the transudation of blood through the peritoneal surface. Ectopic endometriotic lesions can also change the medium to contribute to the definition of the local environment of the…
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Family history of endometriosis and its characteristics
By Selma Oransay
Depression and migraine are two familial disorders affected by menstrual cycle and endometriosis patients have an increased likelihood of suffering from these comorbidities. A correlation of endometriosis, migraine and depression has been already reporteed in the literature, however a link for…
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Is continuous hormonal treatment safe and healthy method for endometriotic patients?
By Selma Oransay
One of the studies related to the search for new markers in pathophysiologic causes of endometriosis is circulating microparticles and their subset "tissue factor". In response to damage, activation, or apoptosis, these microparticles are found in human plasma, urine, saliva,…
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Dienogest versus combined oral contraceptives treatment in postoperative endometriosis care
By Selma Oransay
Dienogest is a synthetic progestin derivative, like oral contraceptives, used to prevent endometriosis recurrence after surgery. Randomized clinical trials verified a significantly higher reduction in endometriotic lesions, clinical symptoms, and improved quality of life obtained when dienogest was given to…
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What causes pelvic pain? Androgens or estrogens?
By Selma Oransay
A comparison between women and men reveals that women suffer more pelvic pain. This reality raises the possibility of the pain-relieving effect of testosterone or androgens. It would be a wise solution to investigate how androgens affect pain at different…
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An Overview on Treatment of endometriosis
By Selma Oransay
There are different guidelines by different gynecological societies for the diagnosis and treatment of endometriosis, which is an extremely complex illness. Kalaitzopoulos and Samartzis et al. from Switzerland worked on and compared six national and two international widely used guidelines to…
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By Eylül GÜNPharmacological Therapy for Endometriosis Pain
By Eylül GÜN
The negative effects of endometriosis on women’s quality of life are indisputable. Women who suffer from endometriosis might have to deal with problems in many aspects such as psychological, sexual, social, and economic. Pain which is one of the most…
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Postoperative long-term estro-progestin therapy for endometrioma
By Selma Oransay
After the removal of ovarian endometriomas, the major concern is the high recurrence rate of symptoms and endometriotic cysts. The estimated recurrence rate of endometriomas is up to 50% at 5 years after surgery. To prevent the recurrence, postoperatively long-term…
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The peculiarity of adolescent endometriosis
By Selma Oransay
Recent studies showed the prevalence of endometriosis in adolescents with chronic cyclic or acyclic pelvic pain is about 60-70%. Moreover, all stages of endometriosis, including deeply infiltrating endometriosis can be found in this population. Gubbels et al. from the Department…
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Diagnosis and treatment algorithm for endometriosis
By Selma Oransay
Endometriosis is a chronic and progressive disease that affects 25-30% of women between 25-35years, clinicians commonly experience during their gynecologic practice. However, the diagnosis is still late or sometimes incorrect, and this creates severe health problems and worse outcomes. A…
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By Irem OnurThe efficacy of combined hormonal contraception on pelvic pain in endometriosis patients
By Irem Onur
Chronic pelvic pain, which is experienced by more than 33% of endometriosis patients, constitutes a significant challenge for patients and physicians. A new study that appears in the journal Human Reproduction Open has explored the prevalence of endometriosis patients with a history…
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Adolescent dysmenorrhea and future endometriosis
By Selma Oransay
Dysmenorrhoea is typically classified as primary, or secondary due to underlying pathologies like fibroids, endometriosis, adenomyosis or uterine anomalies. Generally, long-term dysmenorrhea is present in endometriotic patient's anamnesis, but until recently, the research to clarify this connection remained retrospective. Knox et…
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By Hale Goksever CelikEndometriosis and female pelvic pain in all aspects
By Hale Goksever Celik
Endometriosis is defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity. The prevalence of the disease ranges between 6-10% in reproductive-aged women. However, endometriosis is more frequently encountered in women with chronic pelvic pain and…
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By Özge ÖzkayaOral Contraceptives and Low-Cost Progestins to Reduce Endometriosis-Associated Pain
By Özge Özkaya
Most women with endometriosis-associated pain did not feel the need to use expensive progestin or undergo surgery. Instead, they were satisfied with a low-cost progestin to treat their symptoms. This is according to a study published in the journal Fertility…
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By Murat OsmanContraceptives for the management of endometriosis pain
By Murat Osman
Endometriosis is a common gynecologic disease that affects many women of reproductive age and is associated with significant morbidity. One of the treatment options for women with endometriosis is the use of oral contraceptives (OCPs) for pain management. However, its…
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Switching to a Low-Cost Progestin May Help Reduce Endo Pain When Oral Contraceptives Won’t Work
By Özge Özkaya
The majority of women with endometriosis-associated pain were satisfied to have switched to a treatment with norethisterone acetate or NETA, a synthetic, orally active progestin, when their oral contraceptive was ineffective, found a study published in the journal Reproductive Sciences.…
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By Kasthuri NairHormonal Contraceptives and the Risk of Breast Cancer
By Kasthuri Nair
A study titled “Contemporary Hormonal Contraception and the Risk of Breast Cancer” was recently published in The New England Journal of Medicine and was immediately picked up and summarized by many well-known newspapers and broadcasting journals, including but not limited…
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