Could brain-derived neurotrophic factor (BDNF) be a potential marker of endometriosis ?
Medical student Kyana Jafarabady and academicians from several medical centers in Iran have published their database research on Brain-derived neurotrophic factor (BDNF) in endometriosis patients in a recent issue of BMC Women’s Health. BDNF is a neurotrophin that plays an important…
Key Points Lay SummaryEndometriosis and the risk to have mental disorders
The most common clinical findings of endometriosis patients are pelvic pain and fertility problems, resulting in impairment of quality of life. These women are also affected regarding psychological health due to disease-associated symptoms. Dr. Wang et al., from Taiwan, published…
Key Points Lay SummaryEfficacy of Uterine Artery Blockage in Endometriosis Management
Dr. Li Ma and associates from Liaoning, China have published their results of a computerized database search on the role of uterine artery embolization in endometriosis in a recent issue of the periodical “Computational Intelligence and Neuroscience”. Currently, the management…
Key Points Lay SummaryAre the studies based on the nationwide databases more accurate?
One of the most common localizations of endometriosis is the ovaries, and therefore, ovarian endometriomas are among the most surgically treated endometriotic lesions. Dr. Roman from Denmark has recently written an editorial about the surgical interventions on ovarian endometrioma and…
Key Points Lay SummaryA comprehensive review on the etiopathogenesis of endometriosis
Endometriosis, being a heterogeneous disease has a highly complex etiopathogenesis. A multicenter comprehensive review on this important subject from Italy, Germany, and the USA by Lagana and associates, was recently published in the "International Journal of Molecular Sciences" an open-access journal. Computerized…
Key Points Lay SummaryEndometriosis Knowledgebase
Several studies have pointed to possible genetic factors in endometriosis. Targeted gene-based and high-throughput methods such as Genome-Wide Association Studies (GWAS) have been previously employed to identify endometriosis-associated genes. However, the accuracy of these data are difficult to evaluate and…
Key Points Lay SummaryAssociation between endometriosis and autoimmune disorders is not clear yet
Endometriosis is a common disorder that may affect up to 10% of women of reproductive age. The causes of endometriosis are largely unknown but abnormalities in immunity have been suggested to explain the origin of ectopic endometrial tissues. Evaluation of…
Key Points Lay SummaryHow Artificial Intelligence Can Improve Our Understanding of the Genes Associated with Endometriosis.
Endometriosis is a disease characterized by the development of endometrial tissue outside the uterus. A number of studies have shown that endometriosis could have a genetic basis and numerous genes have been studied and proposed to help explain its pathogenesis.…
Key Points Lay Summary