Gluten-free diet fot endometriosis-associated gastrointestinal symptoms
Women with endometriosis often report gastrointestinal symptoms such as bloating, constipation, diarrhea, and abdominal cramping,may have a negative impact on women’s lives having endometriosis and which can mimic irritable bowel syndrome (IBS) leading to potential misdiagnosis. A commonly suggested dietary…
Key Points Lay SummaryWhy we should prefer nerve-sparing surgery in deep endometriosis?
Despite its benign nature, deep endometriosis can mimic malignant processes and infiltrate multiple organs, blood vessels, ligaments, and nerves within the pelvis. When conservative medical management fails, the need for surgical excision of endometriotic lesions arises. The surgeons aim to…
Key Points Lay SummaryQuantification of nerve bundle density as a biomarker for endometriosis utilizing PGP9.5 immunostaining
Scientists from Netherlands and Canada have published their authentic study on immunohistochemically assessed nerve fiber bundles of endometriotic tissues in a recent issue of Frontiers in Reproductive Health. Endometriotic tissues have nerve fibers which are stimulated in inflammatory processes leading…
Key Points Lay SummaryGluten Intake May Not Have an Effect on Endometriosis
Carbohydrate quality and certain types of fiber such as total vegetable and cruciferous vegetable fiber seem to be associated with endometriosis in women before menopause, found a new study published in the Journal of Nutrition. According to the study, it…
Key Points Lay SummaryIs the presence of nerve fibers in the endometrium associated with endometriosis?
Endometriosis is a common disease in reproductive women and diagnostic imaging have a limited role in its diagnosis. The gold standard diagnostic method remains to be the histopathological examination of the tissue obtained via laparoscopy. One of its most common…
Key Points Lay SummaryNew Signaling Pathway Could Be Crucial in the Development of Endometriosis
RAMP1 signaling is crucial for growth and blood and lymphatic vessel formation in endometrial tissue, according to a new study published in the Journal of Cellular and Molecular Medicine. This suggests that blocking RAMP1 could be a new way to…
Key Points Lay SummaryThe impact of laser vaporization on reproductive outcomes in women with endometrioma
Despite extensive research, the optimal method for the management of endometriosis still remains unclear. Excisional surgery is claimed with a more favorable outcome than drainage and ablation regarding the recurrence of disease and symptoms. On the other hand, cyst vaporization…
Key Points Lay SummaryA novel neurotransmitter, Ninj1, has been found to be expressed in endometriosis
Chronic inflammation is involved in the pathogenesis of endometriosis and adenomyosis, and inflammatory cytokines such as IL-1b are highly expressed in them. Inflammation and subsequent hyperinnervation are involved in the pathophysiology of pain generation. High levels of expression of various…
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