By Eylül GÜNmicroRNA signatures as a non-invasive diagnostic tool for peritoneal endometriosis
By Eylül GÜN
Using microRNA (miRNA) signatures obtained from bodily fluids as a non-invasive diagnostic tool for endometriosis has recently emerged as a useful method. Endometriosis remains an underdiagnosed disease, especially with subtypes such as peritoneal endometriosis which presents with non-specific symptoms. Researchers…
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A new potential biomarker proposal from leukorrhea of endometriosis patients
By Eylül GÜN
Endometriosis is typically diagnosed through laparoscopic surgery, which can be invasive and discourages some patients from participating. Therefore, there is a need for a non-invasive diagnostic method. Exosomes, small vesicles containing biological information, can be found in almost every type…
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Rhein usage in endometriosis: A potential new therapeutic agent
By Eylül GÜN
The invasive nature of endometriosis has prompted scientists to find preventative and curative methods. The progression and proliferation of endometriotic lesions are being studied extensively. As one of the agents used in Chinese herbal medicine for inflammatory disorders, rhein is…
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Exploring a bonafide biomarker to predict endometriosis
By Eylül GÜN
Endometriosis is a complex disease affecting many women in the reproductive age group. As it is important to figure out the mechanisms responsible for the disease, it is also crucial to identify biomarkers that can be used in the diagnosis…
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MicroRNAs in the pathogenesis of endometriosis and infertility
By Eylül GÜN
The gold standard in the diagnosis of endometriosis is laparoscopy and histopathological diagnosis, however search for a non-invasive method has been ongoing. Some biomarkers such as Cancer Antigen 125 have been thought to be useful, but because of their low…
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By Ellen TumimbangNon-coding RNAs and Endometriosis
By Ellen Tumimbang
Non-coding RNAs may have a fundamental role in the development of endometriosis. Non-coding transcripts have regulatory roles in the expression of protein-coding genes, thus regulate several signaling pathways. Based on their length, these non-coding RNAs are classified into two main classes:…
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By Dr. Youngran ParkMicroRNA Inhibitor as an Endometriosis treatment
By Dr. Youngran Park
Endometriosis is a well-known estrogen-dependent gynecological disorder. This disease affects approximately 20% to 50% of infertile women and 10% of reproductive-aged women resulting in infertility and pelvic pains. In order to find endometriosis-specific treatment, various studies have been tried to…
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Anti-proliferative and anti-inflammatory effects of "Quercetin" on endometriosis
By Dr. Youngran Park
Quercetin is a major flavonol that is mainly derived from capers and involves a daily consumption of approximately 25–50 mg through various vegetables. In recent studies, Quercetin is reported as a functional compound in obesity, diabetes and cardiovascular diseases. This compound…
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Non-coding RNAs in endometriosis
By Dr. Youngran Park
The pathophysiological mechanisms causing the development of endometriosis, which is a heterogeneous disease remain enigmatic, and a lack of effective biomarkers necessitates surgical intervention for diagnosis. Non-coding RNA (ncRNA) molecules, which are important regulators of cellular function, have been implicated…
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Epigenetic regulation of the pathological process in endometriosis.
By Dr. Youngran Park
Epigenetic mechanisms have been recognized as important players in the development of a broad range of human diseases including endometriosis. A growing body of evidence shows that the remodeling of retrograde endometrial tissues to the ectopic endometriotic lesions involves multiple epigenetic…
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By Ezio RosatoNew Molecular Targets for the Treatment of Endometriosis-Associated Pain
By Ezio Rosato
The study identifies potential new targets for alleviating chronic pelvic pain that afflicts many women with endometriosis. A new study published in the scientific journal Redox Biology shows that molecules called microRNAs could be a potential new target to combat…
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