Gut Microbiota and Endometriosis; new kid on the block!
Dr. Anjeza Xholli and colleagues from the University of Genova, Italy, conducted a comprehensive review on the potential impact of gut microbiota on gastrointestinal symptoms in endometriosis patients, publishing their findings in Pharmaceuticals, in the leadership of Dr.Cagnacci. Approximately 90% of…
Key Points Lay SummaryAssessing endometrial receptivity using menstrual blood samples in patients undergoing in-vitro fertilization
Endometrial receptivity is the endometrium's capacity to allow the embryo the chance to adhere, infiltrate, and develop while ensuring an ideal microenvironment. When impaired, it is one of the two major factors contributing to infertility along with embryo quality by…
Key Points Lay SummaryIs there a component of "microflora imbalance" in endometriosis?
Dr. Oishi and colleagues from Ryukyus and Mie Universities, Japan, published a prospective cohort study on the microbiota of the female genital tract in the journal "Reproductive Medicine and Biology". Recent studies have found a small number of bacteria in…
Key Points Lay SummaryEndometriosis, pelvic inflammatory disease and ovarian cancer
Endometriosis is a locally aggressive and chronic inflammatory disease and it is now known that with various genetic pathways it creates susceptibility to certain cancers, the most common being ovarian cancer. Pelvic inflammatory disease on the other hand creates a…
Key Points Lay SummarySmall chain fatty acids produced by gut microbiota: Could that be the missing milestone for endometriosis
Endometriosis is a worldwide problem but still, the underlying mechanism and optimal treatment options are controversial. In the study conducted by Sangappa B Chadchan et al., the researchers investigated the possible relationship between gut microbiota and endometriosis. A study published…
Key Points Lay SummaryThe relationship between microbiota and endometriosis
Endometriosis is a multifactorial and complex disease that results in an inflammatory state. This persistent inflammatory state is known to cause immune dysregulation. In the immunopathogenesis of endometriosis, activated macrophages, increased neutrophils, impaired natural killer cells, altered T-cell differentiation, and…
Key Points Lay SummaryThe role of microbiota in the etiopathogenesis of endometriosis
Endometriosis is an estrogen-dependent disease that is commonly diagnosed in reproductive-aged women. Although many advanced types of research about the etiology, differential diagnosis and treatment have been performed, it still remains an enigmatic disease. Dr. Bedaiwy, a scientist and physician…
Key Points Lay Summary