By Selma OransayA review for genetics of endometriosis.
By Selma Oransay
There is an increased risk of developing endometriosis among first-degree relatives, which can raise suspicions of the role of genetic factors in endometriosis. Genome-wide association studies and next-generation sequencing have identified numerous genetic loci and variants relating to the disease.…
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By Bahar YukselEconomic burden while living with endometriosis.
By Bahar Yuksel
Endometriosis is a debilitating disease when all the symptoms are considered. Besides mental and physical effects, the economic burden is also a problem for the patients. In the study conducted by Josep Darbà et al, the costs of endometriosis have…
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By Özge ÖzkayaResearch Identifies Blood Proteins Associated With Endometriosis in Adolescents
By Özge Özkaya
Proteins related to angiogenesis or the formation of new blood vessels and cellular migration are enriched and more active in the blood of adolescents with endometriosis compared to healthy controls. These are the findings of a new study published in…
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What is the cause of Dienogest-resistance in patients with endometrioma?
By Selma Oransay
Endometriosis may cause infertility in women, leading to adhesions in the pelvis, besides affecting the ovaries. Clinicians concern about the child-bearing desire of their patients when treating them surgically or with hormonal therapy. Dienogest (DNG) is a kind of progestin,…
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By Dr. Youngran ParkMachine Learning Classifiers for Endometriosis
By Dr. Youngran Park
Endometriosis is a complicated gynecological disorder that affects about 176 million women worldwide. It significantly impairs mental and physical quality of life in patients but the etiology is poorly understood. Endometriosis also causes a large economic burden due to loss…
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Searching new biomarkers for endometriosis
By Selma Oransay
This recent article published in Advances in Clinical Chemistry, is an overall summary of characteristics, physiopathological theories, diagnostic approaches and variety of biomarkers to diagnose endometriosis and penned by Coutinho et al. from Universidade Federal de Juiz de Fora, Belo Horizonte,…
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By Murat OsmanDevelopment of Less Invasive Diagnostic Tests for Endometriosis Through Proteomics
By Murat Osman
Proteomics is a field which utilizes various methods to carry out large-scale studies of proteins. Due to the inherent nature of the field, proteomics focuses on the identification, localization, and functional analysis of the protein make-up of a given type…
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Endometriosis Development: Pathogenesis and genomics
By Selma Oransay
In this review recently published in the International Journal of Molecular Sciences, Baranow et al from Saint Petersburg, Russia, hypothesize the existence of an endometriosis development genetic program (EMDP) that governs the origin of endometrium stem cells programmed for endometriosis; their transition…
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By Yu YuDetecting endometriosis using peripheral blood
By Yu Yu
Laparoscopic visualization of endometriotic lesions with histological confirmation is the gold standard for the diagnosis of endometriosis. However, this diagnostic procedure, due to the need for laparoscopy and variability of disease/symptoms, can have a major delay up to 8-10 years…
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By Kasthuri NairKey to Understanding Ovarian Endometriosis may lay in the Peptides
By Kasthuri Nair
Xue et al. recently published a paper titled “Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis” in Cellular Physiology and Biochemistry. The research group from various departments of Nanjing Medical University wished to better understand the pathogenesis of…
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Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.
By Yu Yu
Metabolites are the intermediates and products of metabolism from our body. Increasingly the study of metabolite content in biological systems can be used to derive useful information to identify disease-related markers, such as the use of glucose in the blood…
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