By Selma OransayEndometriosis: Investigating Theoretical Causes and Pathogenesis
By Selma Oransay
Understanding the etiology of endometriosis is crucial for preventing its occurrence and minimizing the significant health burdens it imposes on women. As current treatment options are limited and often lead to severe side effects, identifying potential causes can empower women…
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Intrinsic Potential Factors in Retrograde Menstruation
The mechanistic model of endometriosis pathogenesis suggests that anatomical factors promoting retrograde menstruation are crucial and biologically sound. This model is supported by the strong link between obstructive Müllerian anomalies and endometriosis, indicating a causal relationship between the amount of…
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Retrograde Menstruation Theory Through Müllerian Anomalies
By Selma Oransay
The pathogenesis of endometriosis is still under debate. Sampson also described this condition as "developmentally misplaced endometrial tissue" in 1925. To evaluate the theories of pathogenesis, Vercellini et al. from the Academic Center for Research on Adenomyosis and Endometriosis at…
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Any link between endometriosis and neonatal uterine bleeding?
By Selma Oransay
A Medline search using the keywords " neonatal uterine bleeding," " pathophysiology," and "premenarche" was made by Dr. Habiba et al. from the Department of Health Sciences, University of Leicester, Leicester, UK. A total of 2264 articles were collected, and…
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By Nasuhi Engin AydinReviewing all you want to know on endometriosis !
By Nasuhi Engin Aydin
Academicians from the International University of Sarajevo, Bosnia, and Lincoln Medical School, UK have written a comprehensive updated review on endometriosis covering many aspects of endometriosis and published their paper as an open-access manuscript in the journal “Pathology-Research and Practice”. …
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Review of neutrophil based scientific research in endometriosis
By Nasuhi Engin Aydin
Xinlei Wang and associates from Jilin University, Changchun, China, have published a comprehensive review on the pathogenetic role of neutrophils in endometriosis in a recent issue of the periodical “Mediators of inflammation”. As a common inflammatory condition where endometrial tissue…
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By Eylül GÜNSexual activity during menstruation: Any impact on endometriosis development?
By Eylül GÜN
Retrograde menstruation is among the theories for the etiology of endometriosis and there is a hypothesis that sexual activity during menstruation could potentially increase retrograde menstruation, leading to the implantation of endometrial tissue in other areas and consequently increasing the…
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By Özge ÖzkayaWhy Do Some Women Develop Endometriosis While Other Don’t?
By Özge Özkaya
Chemotaxis by natural killer cells as well as cytotoxicity is significantly decreased in the peritoneal cavity of women with endometriosis, according to a new study published in the American Journal of Reproductive Immunology. This means that antigens that enter the…
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By Yu YuEndometriotic mesenchymal stem cells may promote endometriosis
By Yu Yu
The cause of endometriosis is still debatable. Many researchers have accepted that retrograde menstruation, where the endometrial fragments released during menstruation attach and colonize the ectopic locations, is the most plausible reason. However, the numbers just do not add up.…
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Fallopian tubes and endometriosis
By Selma Oransay
There are multiple theories to explain the pathogenesis of endometriosis, among which the most popular one is Sampson's retrograde menstruation theory. The role of endometrial stem cells/progenitors are widely studied to support the origin of ectopic lesions in recent decades.…
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By Hale Goksever CelikEndometriosis by Race
By Hale Goksever Celik
Endometriosis is usually diagnosed in reproductive-aged women with an incidence of approximately 10%. The most common presenting symptoms are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility in patients with endometriosis. Some risk factors have been identified for the development of…
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Defective “ferroptosis”: a new pathogenetic explanation of endometriosis
By Nasuhi Engin Aydin
Dr. Ng and associates from Tufts University School of Medicine, Boston, USA made a comprehensive review of the role of the iron element in the development of endometriotic lesions. Though iron element is essential for cell survival, and its deficiency is important…
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By Dr. Youngran ParkEndometrial single cells to contribute preexisting endometriosis.
By Dr. Youngran Park
Endometriosis is an estrogen-dependent inflammatory disease. This disease affects approximately 10% of reproductive-aged women and 20% to 50% of infertile women. Multiple hypotheses have been proposed for the origin of endometriosis. Retrograde menstruation is believed to take part by the…
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By Timur SeckinA Brief Review of Endometriosis
By Timur Seckin
Endometriosis is a common disease among women of reproductive age. It is more frequently seen among women without prior pregnancies, women with a family history of endometriosis, and women with abnormal menstrual periods. Peiris et al., researchers from the United…
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By Kasthuri NairMenstrual Effluent Can Change the Future of Endometriosis
By Kasthuri Nair
During Endometriosis Awareness Month, Warren et al. published a paper entitled “Analysis of menstrual effluent: diagnostic potential for endometriosis” in Molecular Medicine. This paper relies heavily on the theory of retrograde menstruation, where menstrual effluent flows into the peritoneal cavity.…
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