By Nasuhi Engin AydinEndometriosis and Ovarian Cancer: A Genetic Connection
By Nasuhi Engin Aydin
Academicians Zhang and Yan from Ningbo University, Zhejiang, China, have recently published a pivotal study in Scientific Reports examining the cancer risk associated with endometriosis. Endometriosis, a chronic condition affecting approximately 6–10% of women worldwide, significantly diminishes quality of life…
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By Selma OransayAn observational study on predicting endometriosis recurrence risk.
By Selma Oransay
Endometriosis presents in various ways, and improper management can lead to recurrence. Studies show that the recurrence rate can range from 6% to 67%. Factors that may increase this risk include having severe or deep forms of the disease, being…
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By Özge ÖzkayaPreterm Birth Risk Higher Among Women With Endo
By Özge Özkaya
Pregnant women with endometriosis have a higher risk of having a premature baby and other poor pregnancy outcomes compared to those without the disease, according to a new study published in the scientific journal Fertility and Sterility. This finding highlights the…
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Vitamin D Levels Associated With Endometriosis Risk
By Özge Özkaya
Endometriosis is inversely correlated with the levels of 25-hydroxyvitamin D3 in the serum, according to a new study published in the scientific journal PLoS One. However, more research is necessary to establish a causal link between the disease and vitamin…
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Neonatal uterine bleeding at birth and endometriosis later in life
By Selma Oransay
In the first few days after birth, some female newborns bleed from the vaginal route, and this is called newborn uterine bleeding. The overt and occult neonatal uterine bleeding prevalence rates are 3-5% and 25-60% retrospectively. The causative risk factors for…
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By Eylül GÜNRisk of endometriosis and related occupational factors among working women
By Eylül GÜN
As a debilitating disease, endometriosis is well known to have effects on the patient's overall quality of life. Various studies have consistently reported that working women face an increased risk of endometriosis growth. Lee et al. from Korea conducted a…
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Study Finds Link Between Exposure to Pollutants and Increased Riks of Endometriosis
By Özge Özkaya
High concentrations of polycyclic aromatic hydrocarbons in urine may be associated with a higher risk of endometriosis, according to a new study published in the scientific journal Environmental Science and Pollution Research. The study also found that the concentration of…
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By Hale Goksever CelikA non-invasive test to determine the risk of endometriosis in women having chronic pelvic pain or unexplained infertility
By Hale Goksever Celik
Women having endometriosis may suffer from chronic pelvic pain and/or infertility, both of which diminish the quality of life in these women. Minimalization of the time between the onset of symptoms and diagnosis is essential to improve patients’ lives. However,…
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By Bahar YukselPregnancy and Endometriosis: The Hidden Risk of Gestational Diabetes
By Bahar Yuksel
Getting pregnant with endometriosis may be challenging. Besides, that pregnancy is a high-risk pregnancy. According to the recent meta-analysis led by Dr.Vigano, the risk of gestational diabetes increases in endometriosis patients. The study performed database searches on PubMed, Medline, Embase, and…
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Exploring the Potential Impact of Prenatal Testosterone on Endometriosis
By Bahar Yuksel
The exact causes of endometriosis still remain uncertain but emerging evidence suggests that prenatal factors may contribute to its development. In the review study by Bernard J Cresp et al, the authors discuss the hormonal environment during prenatal development and…
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Breastfeeding Seems to Protect Both Mother and Baby From Endo
By Özge Özkaya
Breastfeeding seems to decrease the risk of endometriosis, according to a new study published in the scientific journal Breastfeeding Medicine. Similarly, there seems to be a negative association between ingesting breast milk and the risk of developing endometriosis later in…
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Scientists Try to Understand Consequences of Genetic Changes in Endometriosis
By Özge Özkaya
The protocol of the "Endometriosis Research Queensland Study" has been published in the scientific journal BMJ Open. The aim of the study is to collect endometrial tissue associated with the disease and chart its genetic architecture. This way, the researchers aim to…
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Social Support is a Predictor of Resilience in Women with Endometriosis
By Özge Özkaya
Satisfying social support and good mental health are key resources for resilience among patients with endometriosis, according to a new study published in the Journal of Clinical Medicine. “The results of this study may assist in the identification of women…
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Taller Girls More Likely to Have Recurring Endometriosis
By Özge Özkaya
Adolescents who are taller and have three or more lesions are at a higher risk of endometriosis recurrence following surgery, according to a new study by Chinese researchers published in the Journal of Obstetrics and Gynaecology. They should, therefore, be…
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The association between severe endometriosis and venous thromboembolism
By Hale Goksever Celik
For clarifying the issue of whether endometriosis patients are at risk for venous thromboembolism due to both their local immune and inflammatory responses and hormonal treatments, Wiegers et al, from the Netherlands, published an explorative cohort study entitled “Risk of…
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Study Identifies Factors Associated With Risk of UrinaryTract Endometriosis Recurrence
By Özge Özkaya
Being younger than age 25 and having an autoimmune disease are significant predictors of the recurrence of urinary tract endometriosis after surgery according to a new study published in the Journal of Minimally Invasive Gynecology. Adjuvant hormonal therapy, on the…
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A search for a marker to show the malignancy risk of endometriomas
By Bahar Yuksel
The premalignant features and precursors that show the malignant potential in endometriomas are not well-known. In the systematic review conducted by Ludovica Bartiromo et al, the markers for malignant transformation have been analyzed and recently published in a recent issue of…
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Geography May Influence Risk of Endometriosis
By Özge Özkaya
The risk of developing endometriosis seems to be geographically heterogeneous across France, according to results from a study published in the journal Scientific Reports. The study identified 20 high-risk hotspots around the country. These showed similar results for non-adenomyosis endometriosis…
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The incidence of ovarian cancer after histologically diagnosed endometriosis.
By Selma Oransay
Ovarian cancer has the highest mortality rate among gynecologic cancers. Furthermore, these patients are generally diagnosed in advanced stage due to their non-symptomatic nature. Therefore, preventative strategies have enormous importance for the management of ovarian cancer. Dr. Hermens and colleagues…
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Which of the suggested environmental risk factors are indeed related to endometriosis?
By Eylül GÜN
Endometriosis is a complex disease with genetic and environmental factors in its poorly understood pathogenesis. Even though many epidemiological studies in the literature have proposed several risk factors, the lack of clear establishment and modification of these potential risk factors…
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Uterine cancer risk in "endometriosis" and "adenomyosis"
By Selma Oransay
Adenomyosis and endometriosis share similar characteristics, and endometriosis is reported to have an increased risk of ovarian cancer. However, the risk of uterine cancer is not clear yet. Hermens and colleagues from Catharina Hospital, from the Netherlands, designed a population-based…
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Chemical Found in Self-Care Products May Be Linked to Endometriosis
By Özge Özkaya
There may be a link between exposure to phthalates and endometriosis according to a new study published in the Journal of Assisted Reproduction and Genetics. Although more research is needed, these findings could be translated into clinical practice according to…
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Endometriosis and Rheumatoid Arthritis, Could There Be a Link?
By Özge Özkaya
Patients with endometriosis have a higher risk of rheumatoid arthritis according to a study published in the journal Rheumatology. This finding suggests that rheumatologists should be especially mindful of the possibility of underlying endometriosis when treating women with rheumatoid arthritis.…
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Factors affecting complications and the recurrence of operated deep infiltrating endometriosis
By Selma Oransay
Deep infiltrating endometriosis is classified as penetrating the endometrial tissues more than 5 mm deep on the peritoneal surface, mainly uterosacral ligament, rectovaginal septum, ovarian fossa, pelvic peritoneum, bowels, ureters, and bladder. Treatment of the disease depends on the need…
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Endometriosis and susceptibility to COVID-19
By Nasuhi Engin Aydin
Dr. Moazzami and associates from Pars Advanced and Minimally Invasive Medical Manners Research Center, Tehran, Iran have published their results on COVID-19 in endometriosis patients in the medical journal named "BMC’s Women’s Health". COVID-19 is still an emerging critical global health problem…
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Cancer risk Evaluation in Korean Endometriosis Cohort
By Bahar Yuksel
The relationship between endometriosis and cancer has always been challenging. The previous studies revealed an increased risk in endometriosis-associated ovarian cancers regarding the alterations in cancerogenic genes or by the effect of iron and hem coming with retrograde menstruation and…
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Could Cosmetics and Personal Care Products Increase the Risk of Endometriosis?
By Özge Özkaya
The use of cosmetics and personal care products may be increasing the risk of endometriosis according to a study by Spanish researchers that was published in the journal "Environmental Research". This finding suggests that restricting the use of these products may…
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Risk Factors Associated with Ureteral Endometriosis
By Özge Özkaya
Patients with severe endometriosis, uterosacral ligament deep involvement with endometriosis lesions of 3 cm in diameter or more, and the presence of previous endometriosis surgery have a significantly higher risk of having ureteral endometriosis. This is according to a study…
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By Timur SeckinTransvaginal sonography for predicting the distance between rectosigmoid endometriosis and the anal verge
By Timur Seckin
For optimal surgery, pre-surgical assessment of the distance between rectosigmoid deep endometriosis lesions and the anal verge (Lesion to Anal Verge Distance-LAVD) is recommended by many specialists. A group of researchers from Norway, Austria, and Australia studied the accuracy of…
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By Dr. Youngran ParkEarly Life Factors for Endometriosis
By Dr. Youngran Park
Endometriosis affects approximately 10% of reproductive-aged women. Despite the significant impact, the etiology of endometriosis is still unclear. A recent systematic review of 15 studies of adolescents found that overall 65% of girls undergoing laparoscopic investigation were diagnosed with endometriosis.…
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Impact of Genetic Variations in Endometriosis
By Dr. Youngran Park
Endometriosis is an estrogen-dependent disorder. This disease affects approximately 7% to 10% of reproductive-aged women and causes negative impacts on society. The underlying causes are unclear; therefore, the understanding of this disease remains a major clinical challenge. Endometriosis has a…
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Endometriosis Severity and Complication Risks Following Laparoscopic Surgery
By Özge Özkaya
In a research article published in the journal Acta Obstetricia et Gynecologica Scandinavica, researchers at Brigham and Women's Hospital in Boston, Massachusetts suggested that the severity of endometriosis could not be a predictor of the risk of post-operative complications. In…
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Endometriosis and atherosclerotic cardiovascular disease
By Selma Oransay
Endometriosis and atherosclerotic cardiovascular disease show the same pathologic mechanism in terms of endothelial dysfunction. Tan et al. from the Department of Obstetrics and Gynecology, the University of British Columbia, Vancouver, Canada reviewed the literature aiming to determine whether women…
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Does the Severity of Endometriosis Increase the Risk of Complications Following Surgery?
By Özge Özkaya
The severity of endometriosis cannot predict the risk of complications after laparoscopy. Instead, the complexity of the surgical procedure itself may increase the risk of complications. This is according to a study published in the journal "Acta Obstetricia et Gynecologica Scandinavica".…
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Factors affecting risk of ovarian endometriosis malignancy
By Özge Özkaya
Getting married when older, having had ovarian endometriosis for longer, giving birth in a shorter time, and other complications in the uterus that are benign may all increase the risk of ovarian endometriosis malignancy. This is according to a study…
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By Yu YuYogurt and ice cream consumption during adolescence may reduce endometriosis
By Yu Yu
Dietary factors may affect the development and severity of endometriosis because of estrogen, prostaglandin metabolism, inflammation, or smooth muscle contractility. Studies investigating the relationship between diet and endometriosis have focused on women’s dietary intake during adulthood. For example, the higher…
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Baby Years and the Risk of Endometriosis
By Özge Özkaya
Early-life factors such as whether a baby was breastfed, have had vaginal bleeding at birth, or whether or not their father was a smoker may be associated with her risk of developing endometriosis in later life. This is according to…
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By Murat OsmanENDORECT scoring system to identify patients at risk for rectosigmoid endometriosis
By Murat Osman
Patients who suffer from endometriosis may benefit from a preoperative score that predicts rectosigmoid involvement. A recent paper published by Huchon et al. at Poissy Saint-Germain en Laye, France, recruited 119 women who underwent laparoscopy for endometriosis between 2011 and…
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Another Genetic Polymorphism That May Increase Risk of Endo
By Özge Özkaya
A single letter change in the Epidermal Growth Factor Receptor (EGFR) gene may significantly increase the risk of endometriosis. This is according to a study conducted among women in Southwest China and published in the journal Medicine. Identifying genetic risk…
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Breast cancer incidence in women with endometriosis
By Yu Yu
The relationship between endometriosis and breast cancer remains unclear. Some studies have shown an increased risk of breast cancer among women with endometriosis, while others suggested no change in the risk of breast cancer. Previously, the authors have found that…
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Extra-ovarian malignancies risk among women with endometriosis
By Yu Yu
For some time, an association between endometriosis and subsequent cancer risk have been reported. In particular, scientific evidence has shown that endometriosis is linked with risk of certain ovarian cancer subtypes known as clear cell and endometrioid. Since endometriosis is…
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By Serdar BalciDoes the presence of endometriosis increase the risk of gynecologic malignancies?
By Serdar Balci
Endometriosis shares common risk factors with endometrial carcinoma and ovarian carcinomas such as obesity, type 2 diabetes, hyperestrogenism, and reproductive characteristics. Endometriosis is also known to be a risk factor for gynecologic malignant tumors. In this study, Li et.al. have…
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Further Results From the FEELING Study Published
By Özge Özkaya
Some women are more likely to develop deep infiltrating endometriosis according to the further analysis of the results of the FEELING study. These are women who: are married, are older, have siblings, have had a prior pregnancy, or for whom…
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By Irem OnurEndometriosis in adolescents
By Irem Onur
Dr. Mama S. T. from Cooper University Hospital, Camden, New Jersey, USA, recently has published his review on advances in the management of endometriosis in the adolescent in the journal “Current Opinion Obstetrics and Gynecology”. In adolescence, there is a…
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The comparison of Chinese women in terms of risk factors, genetics and treatment of endometriosis
By Hale Goksever Celik
Endometriosis is characterized by endometrial implants outside of the uterine cavity. There is a wide spectrum of symptoms of this disease including dysmenorrhea, chronic pelvic pain, dyspareunia, extragenital symptoms. The pathogenesis of endometriosis appears to be multifactorial, including ectopic endometrial…
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Managing of endometriosis and associated ovarian cancer risk
By Yu Yu
According to a number of studies, endometriosis is associated with moderate increase in ovarian cancer risk. This risk is elevated in subjects with a long-standing history of untreated ovarian endometriosis. Endometriosis is particularly associated with risk for certain histological subtypes…
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Recurrence of Deep Infiltrating Endometriosis
By Yu Yu
There are mainly three types of endometriotic lesions. These are ovarian endometriosis, superficial peritoneal endometriosis, and deep infiltrating endometriosis (DIE). The latter is often described as a lesion with greater than 5 mm invasion of the peritoneal surface. DIE lesions…
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By Kasthuri NairThe Past, Present, and Future of Diagnosing Endometriosis
By Kasthuri Nair
This review titled “Endometriosis: Epidemiology, Diagnosis and Clinical Management” published in Current Obstetrics and Gynecology Reports examines the distribution and factors associated with endometriosis. The analysis by Parasar, Ozcan, and Terry also delineates potential biomarkers and risk factors that could…
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EFA Medical Conference 2017: "Breast Cancer in Young Women; Early Diagnosis Timely Intervention" Presentation by Dr. Stephanie Bernik
By Kasthuri Nair
Dr. Stephanie Bernik is the Chief of Surgical Oncology of Surgery and General Surgery at the Lenox Hill Hospital. She recently presented at the EFA 2017 Medical Conference, and her presentation was titled “Breast Cancer in Young Women; Early Diagnosis…
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Is there a risk of developing breast cancer for women with endometriosis?
By Murat Osman
Understanding the interplay between the development of breast cancer and the presence of endometriosis and vice versa is complex since many risk factors including hormone or genetic variations and medical treatments have a role in each disease process. Thus, parsing…
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Association between blood inflammatory markers and the risk of endometriosis
By Yu Yu
Previous studies have suggested that aberrant immunologic and inflammatory responses may play a role in the pathogenesis of endometriosis. Peritoneal fluid collected from endometriosis contains elevated immune cells that may enhance the survival of endometriosis by secreting growth factors and…
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By Vishaan NurseyEndometriosis linked with increased risk of cancer and frequency of future surgical procedures
By Vishaan Nursey
The purpose of this data research was to determine how women with endometriosis might be predisposed to other medical conditions later on in their lives. In order to determine if endometriosis affected health outcomes, a group of Scottish researchers collected…
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Is there any association between menstrual pain and ovarian cancer?
By Yu Yu
Inflammation may be important in ovarian carcinogenesis. Epidemiological studies show that inflammatory conditions such as endometriosis and pelvic inflammatory disease have been associated with an increased risk of ovarian cancer, while regular use of non-steroidal anti-inflammatory drugs has reduced associated…
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Exposure to organic pollutants and endometriosis
By Yu Yu
There is increasing evidence suggesting the associations between exposure to endocrine disrupting chemicals and gynecological diseases over the last decade. In rodent and primate experimental models, consistent associations have been previously found between exposure to dioxins and the onset of…
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Endometriosis and Ovarian Cancer Risk
By Yu Yu
Ovarian cancer prevalence in women with endometriosis is higher than the general population. It is often hypothesized that endometriosis-associated malignancies can occur from ovarian endometrioma. This systematic review by Taniguchi highlighted new insights on the relationship between endometriosis and ovarian…
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Asian Women at Higher Risk of Endometriosis and Less Likely to Conceive with IVF but not Because of their Endometriosis
By Özge Özkaya
The rate of endometriosis is higher amongst women of Asian origin confirms a study published in the Journal of Assisted Reproduction and Genetics. In addition, pregnancy rates following fertility treatments are lower in this group of women. However, this does…
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Genetic Variations May Link Risk of Endometriosis and Ovarian Cancer
By Özge Özkaya
Variations in a gene called HNF1B could be linked to the risk of endometriosis, according to a study published in the medical journal Gynecologic Oncology. Previous studies had identified the same genetic variation as a risk factor for ovarian cancer.…
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