By Selma OransayNon-invasive MRI Based Detection of Uterosacral Deep Infiltrating Endometriosis
By Selma Oransay
Deep infiltrating endometriosis (DIE) frequently affects the uterosacral ligaments, with a prevalence of around 70% in affected patients. However, there is no consensus on the imaging anatomy of the uterosacral ligaments (USLs). Currently, the assessment of USL endometriosis is subjective, lacking…
Key Points Lay Summary
By Özge ÖzkayaAnti-inflammatory Diet Feasible in Patients With Endometriosis
By Özge Özkaya
An anti-inflammatory diet is feasible in patients with endometriosis, according to a new study published in the journal Reproductive BioMedicine Online. This is the case especially when identified barriers and facilitators are addressed in an intervention. “ Provision of knowledge, stimulating…
Key Points Lay Summary
By Hale Goksever CelikLifestyle and Environmental Factors in Endometriosis: Current Insights and Future Directions
By Hale Goksever Celik
Endometriosis-associated symptoms such as dysmenorrhea, dyspareunia, chronic pelvic pain have an effect to diminish the quality of life. The physical and mental quality of life of these women is adversely affected. There are several studies evaluating the quality of life…
Key Points Lay Summary
Gluten-free diet fot endometriosis-associated gastrointestinal symptoms
By Hale Goksever Celik
Women with endometriosis often report gastrointestinal symptoms such as bloating, constipation, diarrhea, and abdominal cramping,may have a negative impact on women’s lives having endometriosis and which can mimic irritable bowel syndrome (IBS) leading to potential misdiagnosis. A commonly suggested dietary…
Key Points Lay Summary
Nerve-Sparing Surgery Safe in DIE
By Özge Özkaya
Robot-assisted nerve-sparing modified radical hysterectomy is associated with longer operative times and lower estimated blood loss compared to the conventional laparoscopic approach to treat deep infiltrating endometriosis (DIE), according to a new study published in the scientific journal Archives of…
Key Points Lay Summary
By Nasuhi Engin AydinNanotechnology for endometriosis
By Nasuhi Engin Aydin
Dr.Talukdar from Morehouse School of Medicine, Atlanta, GA, and colleagues have published a timely review of nanoparticle applications in endometriosis. This review appeared in the June 2024 issue of the journal “Nanomaterials”. As envisioned by Professor Ehrlich in the 19th…
Key Points Lay Summary
Impact of Endometriosis Subtypes on Increased Ovarian Cancer Risk
By Özge Özkaya
The risk of ovarian cancer is markedly increased in patients with ovarian endometriomas and/or deep infiltrating endometriosis (DIE), according to a new study published in The Journal of the American Medical Association. These patients should be offered counseling about the risk of ovarian cancer and…
Key Points Lay Summary
Long-term Dienogest Treatment and the Chance of Conceiving With IVF
By Özge Özkaya
It is not clear whether long-term treatment with dienogest before in vitro fertilization (IVF) affects pregnancy and live birth rates in women with endometriosis, according to a new study published in the Journal of Obstetrics and Gynaecology Canada. “Given limited…
Key Points Lay Summary
Monitoring eating behavior is important
By Selma Oransay
The relationship between dietary products and endometriosis gained interest after the recognition that a proper diet can improve pathological and physiological processes. There is also a belief that the benefits of some anti-oxidants may have a therapeutic effect on the…
Key Points Lay Summary
Mediterranean Diet Associated With Less Endometriosis Pain?
By Özge Özkaya
There seems to be a link between pain relief in endometriosis and a Mediterranean diet, according to a new study published in the International Journal of Science. This finding suggests that a Mediterranean diet could help manage chronic pain in…
Key Points Lay Summary
Endometriosis in Asia
By Nasuhi Engin Aydin
Academicians from the University of Philippines led by Dr. Velarde have published a recent review on endometriosis and Asian women in the scientific periodical “Endocrine Connections”. The endometriosis prevalence rate is variable among ethnicities, and Asian women including Filipinos, Indians, Japanese,…
Key Points Lay Summary
Women With Endo Left Alone To Deal With Their Gut Symptoms
By Özge Özkaya
Women with endometriosis had patterns of restrictive behavior, according to a new study published in the European Journal of Obstetrics & Gynecology and Reproductive Biology. They also wanted more professional support to help them manage the gut symptoms associated with the…
Key Points Lay Summary
Dienogest versus combined oral contraceptives treatment in postoperative endometriosis care
By Selma Oransay
Dienogest is a synthetic progestin derivative, like oral contraceptives, used to prevent endometriosis recurrence after surgery. Randomized clinical trials verified a significantly higher reduction in endometriotic lesions, clinical symptoms, and improved quality of life obtained when dienogest was given to…
Key Points Lay Summary
By Eylül GÜNNutritional recommendations for endometriosis patients
By Eylül GÜN
Diet and lifestyle factors have been implicated in the development and progression of endometriosis, in addition to genetic determinants. Piecuch et al. from Poland conducted a review study discussing the importance of different nutrients and nutritional recommendations in endometriosis. The…
Key Points Lay Summary
Autoantibodies Cannot Be Used to Detect Endometriosis Just Yet
By Özge Özkaya
There seems to be no significant difference in the expression of autoantibodies in the plasma or peritoneal fluid of women with endometriosis and those without the disease. This is according to a new study published in the journal Human Reproduction.…
Key Points Lay Summary
Pretreatment With Dienogest Does not Seem to Improve IVF Outcome in Endometriosis
By Özge Özkaya
Treatment with dienogest before in vitro fertilization does not increase the number of mature eggs or improve the rate of pregnancy or live births in women with endometriosis, found a new study published in the scientific journal Gynecologic and Obstetric…
Key Points Lay Summary
Another New Approach Could Help Diagnose deep Infiltrating endometriosis
By Özge Özkaya
Elastography could help distinguish deep infiltrating endometriosis (DIE) nodules from non-endometriotic tissue at different locations, according to a new study published in Ultraschall in der Medizin - European Journal of Ultrasound. The potential of the technique in improving the diagnosis…
Key Points Lay Summary
By Bahar YukselDeep Infiltrating Endometriosis and Adenomyosis have different genetic pathways
By Bahar Yuksel
It is still not defined whether adenomyosis is also a deep endometriosis component or not. In the study conducted by Marshall et al, the researchers compared the gene expression patterns between deep infiltrating endometriosis (DIE) and adenomyosis uteri in order…
Key Points Lay Summary
Endometriosis diet and the quality of life
By Hale Goksever Celik
Women with endometriosis suffer mainly from pelvic pain which results in a negative effect on the quality of life. Although several treatment options have been proposed, some endometriosis patients still have poor quality of life due to pelvic pain. Upon…
Key Points Lay Summary
Integrative medical management of endometriosis
By Selma Oransay
This lecture entitled "Integrative Medical Management of Endometriosis" was presented by Dr. Pinar Kodaman, Director of the endoscopic reproductive surgery program and Assoc. Professor of Clinical ObGyn and Reproductive Sciences at the Yale School of Medicine. In addition to surgery which…
Key Points Lay Summary
Does taking all deep endo nodules out improve fertility?
By Bahar Yuksel
Deep infiltrative endometriosis is an issue that comes to the scene more than before according to detection rates with help of awareness on clinicians. But treating infertility related to endometriosis is still unclear when it comes to DIE patients. In…
Key Points Lay Summary
Diagnostic criteria for uterosacral ligament involvement in endometriosis.
By Selma Oransay
Transvaginal ultrasonography is often used to diagnose endometriosis in suspected women due to its high resolution, low cost, and relatively low discomfort. Histologic confirmation of laparoscopically removed specimens is still the gold standard for appropriate diagnosis. The team led by…
Key Points Lay Summary
TSH receptor antibodies show promising results in the diagnostic workup of endometriosis
By Nasuhi Engin Aydin
Dr. Svensson with collaborators from the Swedish Lund University has published their results on the possible role of TSH receptor antibodies as biomarkers in endometriosis diagnosis in a recent issue of “European Journal of Obstetrics & Gynecology and Reproductive Biology”.…
Key Points Lay Summary
The effect of postoperative hormonal medication preferences on the recurrence rate of endometrioma
By Bahar Yuksel
Endometrioma is the most investigated type of endometriosis. The recurrence after surgery is important regarding its and reoperation’s effect on ovarian functions. In the study conducted by Seung-Hye Choi et al, the researchers questioned the effect of different postoperative hormonal…
Key Points Lay Summary
Gluten Intake May Not Have an Effect on Endometriosis
By Özge Özkaya
Carbohydrate quality and certain types of fiber such as total vegetable and cruciferous vegetable fiber seem to be associated with endometriosis in women before menopause, found a new study published in the Journal of Nutrition. According to the study, it…
Key Points Lay Summary
Evaluation of retrocervical and parametrial deep endometriosis by detailed ultrasonography
By Selma Oransay
The accuracy of ultrasonographic diagnosis of deep endometriosis in the retrocervical and parametrial areas may be poor due to the variable morphology of endometriotic lesions, the complex structure of the posterior parametrial compartment, and the difference in examiners' experience level.…
Key Points Lay Summary
Is it possible to reduce pain by diet in endometriosis?
By Eylül GÜN
Endometriosis-related pain is one of the most common symptoms of endometriosis that significantly affects the patient's quality of life. The peripheral and central sensitization, caused by chronic inflammation activation, may result in referred pain. The pain perception was shown to…
Key Points Lay Summary
Self-Management Strategies for Endometriosis
By Özge Özkaya
Many self-management strategies for endometriosis are not more effective at reducing the symptoms of the disease compared to placebo or hormonal therapies, according to a new study published in the journal Reproductive Sciences. The authors, therefore concluded that “no recommendations…
Key Points Lay Summary
Imaging Techniques Able to Predict Depth of Endometriosis Before Surgery
By Özge Özkaya
Transvaginal ultrasound (TVUS) and pelvic magnetic resonance imaging (MRI) performed by a specialist can accurately predict the depth of rectosigmoid endometriosis before surgery, according to a new study published in the Journal of Minimally Invasive Gynecology. Both approaches are similar…
Key Points Lay Summary![To be or not to be [surgery or hormonal therapies for pain] that’s the question!](/member_files/object_files/endonews.com/2022/02/22/surgery.jpg)
To be or not to be [surgery or hormonal therapies for pain] that’s the question!
By Bahar Yuksel
Deep infiltrative endometriosis is the most challenging type of endometriosis disease. Surgical management is the one that most surgeons prefer for dealing with, while it requires experience and usually causes complications related to the requirement of difficult operative techniques. Thus,…
Key Points Lay Summary
Which one is more effective for the preservartion of postoperative ovarian reserve?
By Selma Oransay
Although cystectomy is the most preferred treatment of endometrioma, it is still a matter of debate as it may cause a reduction in the quality and number of remaining follicles, especially important for women who are planning to conceive. Anti-Müllerian…
Key Points Lay Summary
Effects of Hormonal Contraceptives on Endometriosis Pain
By Özge Özkaya
There is no difference between the oral progestin dienogest and combined oral contraceptive pills in managing pain and increasing quality of life in women with endometriosis, according to the results of a randomized, double-blind, placebo-controlled clinical trial. However, there was…
Key Points Lay Summary
Environmental factors play a role in the development of endometriosis
By Hale Goksever Celik
The proposed mechanisms underlying the development of endometriosis may be classified into three groups: in-situ theory, implantation theories, and induction theories. Genetic, hormonal, environmental, and lifestyle-related factors are also involved as no mechanism is solely responsible for endometriosis development. Although there are…
Key Points Lay Summary
Dietary adjustments do not increase the quality of life of women with endometriosis.
By Özge Özkaya
Even though dietary changes do not seem to increase patients’ quality of life, they lead to a perceived reduction in symptoms. No specific adjustment in the diet increases the quality of life of women with endometriosis, according to a new…
Key Points Lay Summary
Dienogest treatment increases the risk of Endometriosis reoperation rate
By Selma Oransay
The common and accepted therapy of endometriosis is surgery, however medical treatment such as nonsteroidal anti-inflammatory drugs, gonadotropin-releasing hormone agonists, oral contraceptives and oral progestins are used for either relieving pain or to prevent recurrences and reoperation. Due to bone loss and…
Key Points Lay Summary
Non-pharmacological self-care: dietary modifications in women with endometriosis.
By Selma Oransay
The academic interest on the role of diet in endometriosis has grown due to its possible relation with inflammation, estrogenic activity, and menstrual cycles. Multiple dietary strategies and prescriptions are being used to deal with the pelvic pain and gastrointestinal…
Key Points Lay Summary
Not just the pain stops but also the bowel function improves after DIE surgery
By Bahar Yuksel
Bowel endometriosis and the techniques to operate it have always been a challenge. The study conducted by Beraldo et al., from Brazil, highlighted the results of an effective nerve-sparing bowel surgery on endometriosis lesions and its long-term effects on patients. The…
Key Points Lay Summary
It is not that simple: endometriomas are almost never alone
By Bahar Yuksel
Endometriomas are the widely and easily diagnosed type of endometriosis. They are usually treated by gynecologic surgeons and are thought to be alone most of the time. The study conducted by Piriyev et al highlighted the coexistence of extraovarian endometriosis…
Key Points Lay Summary
Progestin suppression for endometriosis before IVF
By Hale Goksever Celik
“Dienogest is a suitable and safe substitute for GnRHa pretreatment in endometriosis patients”, according to the Khalifa et al., from Egypt. Endometriosis is one of the leading reasons for infertility due to decreased oocyte/embryo quality, fertilizability, tubal function, and aberrant endometrial…
Key Points Lay Summary
By Yu YuCancer, is that a real risk?
By Yu Yu
Endometriosis is non-malignant but shares some similar features with cancer, such as the occurrence of local and distant foci, the ability to resist cell death, and the ability to invade other tissues, causing damage to the organs. Endometriosis also generates…
Key Points Lay Summary
What is the cause of Dienogest-resistance in patients with endometrioma?
By Selma Oransay
Endometriosis may cause infertility in women, leading to adhesions in the pelvis, besides affecting the ovaries. Clinicians concern about the child-bearing desire of their patients when treating them surgically or with hormonal therapy. Dienogest (DNG) is a kind of progestin,…
Key Points Lay Summary
Sleep Quality, Lifestyle Factors and Endometriosis
By Hale Goksever Celik
Endometriosis does not only affect the patients by dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. An important issue in these patients, like other chronic diseases, is sleep quality. Youseflu et al., from Iran, published a study entitled “Effects of endometriosis…
Key Points Lay Summary
By Murat OsmanColorectal Deep Endometriosis Resection and Potential Complications
By Murat Osman
A severe clinical form of endometriosis, deeply infiltrating endometriosis (DIE) is characterized by more aggressive endometriotic lesions commonly involving deeper pelvic or gastrointestinal organs. It causes significant quality of life impairment and morbidity and is increasingly associated with infertility. When…
Key Points Lay Summary
Hormone Therapy Before Endometriosis Surgery
By Yu Yu
Hormonal therapy can be effective for endometriosis, although laparoscopic surgery is required for the frequent drug-resistant symptoms. Laparoscopic surgery can markedly improve endometriosis-associated pain. The administration of GnRH agonist prior to endometriosis laparoscopic surgery may be beneficial to improve surgical…
Key Points Lay Summary
The effects of nutrients on endometriosis-related symptoms
By Nasuhi Engin Aydin
A recent literature review from the Netherlands by researchers Emma Huijs and Annamiek Nap, published in "Reproductive Biomedicine Online" puts light on the effects of some nutrients for endometriosis-related symptomatology. Endometriosis has heterogeneous pathogenesis involving genetic, immunological, environmental, and hormonal…
Key Points Lay Summary
Diagnosis and treatment algorithm for endometriosis
By Selma Oransay
Endometriosis is a chronic and progressive disease that affects 25-30% of women between 25-35years, clinicians commonly experience during their gynecologic practice. However, the diagnosis is still late or sometimes incorrect, and this creates severe health problems and worse outcomes. A…
Key Points Lay Summary
How should MRI images be obtained for optimal endometriosis detection?
By Murat Osman
It is well known that the diagnosis of endometriosis for some patients with the chronic pelvic disease is delayed, often for years, due to the disease, patient, and physician-led factors. An area of active study is how ordering physicians can…
Key Points Lay Summary
By Dr. Youngran ParkEarly Life Factors for Endometriosis
By Dr. Youngran Park
Endometriosis affects approximately 10% of reproductive-aged women. Despite the significant impact, the etiology of endometriosis is still unclear. A recent systematic review of 15 studies of adolescents found that overall 65% of girls undergoing laparoscopic investigation were diagnosed with endometriosis.…
Key Points Lay Summary
By Irem OnurMRI findings predicting the need for colorectal surgical treatment of deep infiltrating endometriosis
By Irem Onur
LAY SUMMARY: Brusic A. et al., a group of researchers from Australia, conducted a retrospective study to identify the features of deep infiltrating endometriosis on MRI which have an association with colorectal surgical bowel resection. They have recently published their…
Key Points Lay Summary
Consquences of endometriosis in menopausal period.
By Selma Oransay
Marie-Scemama et al. from Foch Hospital, Suresnes, France, referred to endometriosis and menopause which is an actual cruising topic and recently published it in the journal named "Hormone Molecular Biology and Clinical Investigation". Endometriosis a well-known estrogen-dependent disease has three…
Key Points Lay Summary
Yogurt and ice cream consumption during adolescence may reduce endometriosis
By Yu Yu
Dietary factors may affect the development and severity of endometriosis because of estrogen, prostaglandin metabolism, inflammation, or smooth muscle contractility. Studies investigating the relationship between diet and endometriosis have focused on women’s dietary intake during adulthood. For example, the higher…
Key Points Lay Summary
ENDORECT scoring system to identify patients at risk for rectosigmoid endometriosis
By Murat Osman
Patients who suffer from endometriosis may benefit from a preoperative score that predicts rectosigmoid involvement. A recent paper published by Huchon et al. at Poissy Saint-Germain en Laye, France, recruited 119 women who underwent laparoscopy for endometriosis between 2011 and…
Key Points Lay Summary
Endometriosis pathophysiology: research in genes updated
By Nasuhi Engin Aydin
Endometriosis has a broad spectrum of environmental influences and genetic factors. I In this recently published review article in Experimental and Therapeutic Medicine, Vassilopoulou and associates present information about gene‑gene and gene‑environment interactions involved in endometriosis and discuss the effectiveness…
Key Points Lay Summary
The genetic predisposition to endometriosis
By Hale Goksever Celik
Endometriosis is an estrogen-dependent gynecological disease mostly encountered in reproductive-aged women. Although endometrium is a non-malignant disease, its symptoms can range from mild to severe due to the inflammation that ectopic endometrial tissue forms around itself. The exact etiopathogenetic mechanism…
Key Points Lay Summary
By Demet Candaş GreenCan early-life exposures affect endometriosis development later in life?
By Demet Candaş Green
Endometriosis is a complex disease with possible multifactor contributors. So far, inflammatory, immunogenic, genetic, and environmental factors have all been associated with endometriosis. In addition, it is possible that different types of endometriosis lesions – peritoneal, ovarian, and deep infiltrating…
Key Points Lay Summary
Self-management of endometriosis symptoms: from Australia
By Demet Candaş Green
Effective self-management techniques and lifestyle changes may play an important role in the management of endometriosis symptoms by many women. Due to various reasons such as limited effectiveness of some medications, potential side effects, availability of medical resources, self-desire to…
Key Points Lay Summary
The association between the development of endometriosis and dietary habits
By Hale Goksever Celik
Endometriosis is a chronic disease defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity. The prevalence is found to be approximately 10% in the general population. Endometriosis is associated with infertility, pelvic pain, and increased…
Key Points Lay Summary
Further Results From the FEELING Study Published
By Özge Özkaya
Some women are more likely to develop deep infiltrating endometriosis according to the further analysis of the results of the FEELING study. These are women who: are married, are older, have siblings, have had a prior pregnancy, or for whom…
Key Points Lay Summary
Presumed molecular mechanisms for herbal medicinal therapies in endometriosis
By Nasuhi Engin Aydin
Pharmaceutical agents for the management of endometriosis are associated with side effects and are not completely effective. In regard to this, Bina and associates from Tehran University of Medical Sciences have reviewed extensively the literature for herbal remedies. Herbal medicinal products…
Key Points Lay Summary
Laparoscopic mesenteric vascular and nerve sparing surgery as a tool for DIE resection
By Murat Osman
Endometriosis can be characterized by a wide range of clinical aggressiveness based upon the location, character, and growth of ectopic endometrial implants. As one of the most aggressive forms of endometriosis, deep infiltrating endometriosis (DIE) is known to involve the…
Key Points Lay Summary
Feasibility of MRI-Transvaginal Ultrasound Imaging for Deeply Infiltrating Endometriosis
By Murat Osman
Endometriosis is a disease whereby endometrial tissue is present outside of endometrium. A specific form of endometriosis, Deeply Infiltrating Endometriosis (DIE), is characterized by endometriotic glands that invade through the endometrium and other structures in the pelvis and is associated…
Key Points Lay Summary
Does deep infiltrating endometriosis affect sexual activity?
By Dr. Youngran Park
Endometriosis is one of the most common gynecological diseases in women of reproductive age, and pelvic pain and infertility are the most frequent complications. There are three different type of endometriosis lesions; superficial lesions, deep lesions, and ovarian cysts. In…
Key Points Lay Summary
How Ovarian Endometriomas and DIE affect ART outcomes
By Murat Osman
Previous studies have evaluated the impact of an ovarian endometrioma on ovarian reserve and its impact on the success of assisted reproductive technology (ART) outcomes have controversial results. ART is a method by which a woman’s own hormones are used…
Key Points Lay Summary
Endometriosis involvement of the pouch of Douglas: TVUS vs pelvic exam
By Murat Osman
Deep infiltrating endometriosis (DIE) can lead to a partial or complete obliteration of the pouch of Douglas (POD). POD involvement has been associated with dyschezia, deep dyspareunia, and increased infertility rates. Assessing the extent of endometriosis involvement of the cul-de-sac allows…
Key Points Lay Summary
Will I Have Complications After Endometriosis Surgery?
By Özge Özkaya
The rate of complications after surgery to treat deep infiltrating endometriosis is low, confirmed a study by researchers in Germany. It is important to know whether major or minor complications following surgery are likely to develop and what the outcome…
Key Points Lay Summary
Cosmetics and some household products could be responsible for worsening endometriosis.
By Selma Oransay
A controlled clinical study recently published in the Journal of Human Reproductive Sciences, composed by Nazir et al. from the University of Health Sciences, Lahore, Pakistan. The study compared the blood diethyl hexyl phthalate (DEHP) levels of fifty infertile women laparoscopically diagnosed…
Key Points Lay Summary
A prospective cohort study examining meat and fish consumption and endometriosis risk.
By Dr. Youngran Park
Endometriosis is a benign, estrogen-dependent, gynecologic condition with a prevalence of ~10% in women of reproductive age. There has been an increased interest in the identification of modifiable risk factors for endometriosis including diet. Diet may influence endometriosis risk through…
Key Points Lay Summary
Stenoses in the colorectal anastomose sites after DIE surgery
By Hale Goksever Celik
Deep infiltrating endometriosis (DIE) is a particular form of endometriosis that penetrates at least 5 mm under the peritoneal surface. DIE is primarily located in the rectosigmoid junction and the rectum with an incidence of 70% and 90%, respectively. The…
Key Points Lay Summary
By Kasthuri NairEndometriosis can Adversely Affect Oocyte Quality
By Kasthuri Nair
Kasapoglu et al. recently published a study in Gynecological Endocrinology titled “Detrimental effects of endometriosis on oocyte morphology in intracytoplasmic sperm injection cycles: a retrospective cohort study.” In this paper, they compared the oocytes recovered from women who have endometriosis…
Key Points Lay Summary
Citrus Fruits May Reduce the Risk of Endometriosis
By Özge Özkaya
Eating more fruits, and especially citrus fruits like oranges, and grapefruit may lower the risk of a woman developing endometriosis, found a study published in the scientific journal Human Reproduction. In contrast, some vegetables may increase the risk of the…
Key Points Lay Summary
Long-term Use of Dienogest can Prevent Recurrence of Endometriomas
By Kasthuri Nair
Chandra et al. recently published a paper titled “Clinical experience of the long-term use of dienogest after surgery for ovarian endometriomas” in Obstetrics and Gynecology Science. The publication explored the benefits and repercussions associated with long-term use of dienogest, a…
Key Points Lay Summary
Detection and diagnosis of deep endometriosis in the clinical setting
By Murat Osman
This review aims to evaluate the contribution of imaging techniques including transvaginal sonography (TVS) and magnetic resonance imaging (MRI) to the diagnosis of deep infiltrating endometriosis (DIE). Endometriosis is defined by the presence of endometrial tissue outside the uterus and…
Key Points Lay Summary
Dienogest Use Over A Prolonged Period of Time
By Kasthuri Nair
There are not a lot of treatments on the market for endometriosis; however, Dienogest (DNG), a progestin that has high selective progesterone activity along with low androgenic activity, has been found to reduce endometriosis-associated pain. Lee et al. recently published…
Key Points Lay Summary
Short-term effects of dienogest on ovarian endometriomas
By Murat Osman
First-line treatment of symptomatic, uncomplicated ovarian endometriosis is the use of progestins with or without estrogens such as Dienogest (DNG). These drugs are used to inhibit ovulation and thus reduce the estrogenic environment in which endometriosis relies upon for survival.…
Key Points Lay Summary
EFA Medical Conference 2017: “Literature Review, Our Data, and Case Presentations” by Dr. Karli Goldstein
By Özge Özkaya
Dr. Karli Goldstein started her presentation with a brief literature review on the relationship between endometriosis and breast cancer. She focused on a research article by Dr. Spandidos and colleagues, which was the first epidemiological study that examined the possible…
Key Points Lay Summary
EFA Medical Conference 2017: Welcome Presentation by Dr. Tamer Seckin
By Kasthuri Nair
The first part of the Endometriosis Foundation of America’s 2017 Medical Conference delved into the mission and history of the Endometriosis Foundation of America. The first presenter was Dr. Tamer Seckin, a renowned surgeon, and gynecologist who is also the…
Key Points Lay Summary
Swimming Against the Stream: Is Surgery Worthwhile in Women with Deep Infiltrating Endometriosis and Pregnancy Intention?
By Murat Osman
Management of Deeply Infiltrating Endometriosis (DIE) is further complicated by the implications of affected patients who plan to become or are pregnant. Optimal management in this situation is not standardized due to a lack of randomized trials comparing primary surgery…
Key Points Lay Summary
A New Treatment Time-Table for Controlling Endometriosis-Associated Pelvic Pain
By Kasthuri Nair
It is no secret that Endometriosis is an extremely painful disease. Unfortunately, science has yet to determine a treatment that can effectively treat the disease or the associated pain. In their paper titled “Ethinylestradiol 20 mg/drospirenone 3 mg in a…
Key Points Lay Summary
With so many imaging tools and modalities, which one should be used for endometriosis?
By Murat Osman
Intestinal endometriosis affects 5 to 12% of women with endometriosis and commonly presents as dyschezia, rectal bleeding, cyclic defecation pain, constipation, and diarrhea. Currently, surgical treatment includes segmental rectal resection with colorectal anastomosis, but it is often riddled with complications.…
Key Points Lay Summary
Updates in the Field of Endometriosis: Surgery
By Kasthuri Nair
Surgery is one of the treatment options offered for individuals with endometriosis. With that in mind, there are a variety of surgical procedures that can be offered to an individual with endometriosis. In the chapter titled “Surgery and Endometriosis,” Zanelotti…
Key Points Lay Summary
Updates in the Field of Endometriosis: Genetics
By Kasthuri Nair
This chapter written by Krishnamoorthy and Decherney re-evaluate the literature concerning the genetics of endometriosis. The genetic mechanisms and signaling pathways that led to endometriosis are updated and the tools that help researchers find these abnormal genes and pathways are…
Key Points Lay Summary
First-line surgery followed by ART versus ART alone among women with colon-involving endometriosis.
By Murat Osman
Endometriosis, a disease characterized by the presence of endometrial tissue outside the uterus, may cause pelvic and gynecologic complications that affect fertility in women of reproductive age. Several forms of endometriosis have been observed that are characterized by the varying…
Key Points Lay Summary
Surgical treatment of colonic endometriosis
By Demet Candaş Green
In this study, the authors provide a brief report published in the journal "The American Surgeon" which retrospectively reviewed the therapy outcomes in eight consecutive patients who had a laparoscopic surgical intervention for deeply infiltrating endometriosis (DIE) at Anne Arundel Medical Center. The…
Key Points Lay Summary
Dienogest for Endometriosis
By Kasthuri Nair
Laganà et al. recently published an article in Expert Opinion on Drug Metabolism & Toxicology titled “Clinical dynamics of Dienogest for the treatment of endometriosis: from bench to bedside.” This article explored the benefits of using Dienogest, a progestin, to…
Key Points Lay Summary
Ovarian Endometriomas vs Deep Infiltrating Endometriosis
By Yu Yu
Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) have been described as two disease entities, although they are both characterized by endometrial tissue located outside the uterus. As OMA and DIE look different histologically, it is puzzling what cause their…
Key Points Lay Summary
By Asli Bahadirli TalbottCA-125 may be useful for the diagnosis of deep infiltrating endometriosis
By Asli Bahadirli Talbott
Marco Aurélio Oliveira et al. conducted a prospective study at outpatient gynecology clinic and Endometriosis Treatment Center in Pedro Ernesto University Hospital (Rio de Janeiro State University) between January 2012 and January 2016 with two groups of patients: deep infiltrating endometriosis…
Key Points Lay Summary
Diet & Endometriosis
By Asli Bahadirli Talbott
Diet and the risk of developing endometriosis Current studies examining the modifiable risk factors for prevention of endometriosis are pointing to the development of effective dietary restrictions. Thus understanding the role of nutrition in endometriosis has become critical. In a…
Key Points Lay Summary