By Selma OransayAdenomyosis as a Barrier to Effective Surgery for Dyspareunia in Rectovaginal Endometriosis
By Selma Oransay
Women with endometriosis often experience severe pain during intercourse, known as dyspareunia, which can deeply affect their quality of life and intimate relationships. One form of this condition, rectovaginal septum endometriosis, involves deep, scarred tissue that can cause pain during…
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The prevalence of deep and superficial dyspareunia in women with endometriosis..
By Selma Oransay
Almost half of the women affected by endometriosis experience both superficial and deep dyspareunia. While superficial dyspareunia is less studied, deep dyspareunia is often linked to mechanical pressure on endometriotic lesions or tissue rigidity. To address the sexual difficulties faced…
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Bladder Endometriosis: Current Knowledge and Future Directions
By Selma Oransay
About 70-80% of urinary tract endometriosis occurs in the bladder, particularly affecting the base and dome regions. Endometriotic lesions can penetrate the detrusor muscle either partially or completely. Endometriosis affecting the uterovesical fold peritoneum or deep endometriosis that does not involve…
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By Eylül GÜNEndometriosis relief: How vitamins C and E can make a difference
By Eylül GÜN
Recent studies indicate that oxidative stress significantly contributes to the onset and progression of endometriosis. High levels of reactive oxygen species (ROS) can cause cellular damage and enhance inflammation, leading to the pain associated with the condition. Antioxidants like vitamins…
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Ultrasonographic findings and the clinical symptoms of pelvic endometriosis
By Selma Oransay
Imaging techniques achieve the clinical diagnosis of endometriosis, which affects 10-15% of all women of reproductive age. Suspected patients with clinical history and symptoms need a systemic examination of the uterus, ovaries, adnexa, and peritoneal covering the rectouterine, retrocervical, and…
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Coupled torture due to endometriosis and depressive symptoms
By Eylül GÜN
Endometriosis significantly impacts various aspects of women's lives including their physical and mental health, careers, and social relationships. Physically, it causes chronic pelvic pain and dyspareunia, affecting 5-10% of reproductive-age women and leading to infertility challenges and a substantial percentage…
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By Özge ÖzkayaPotential New Therapeutic Avenue for Deep Endometriosis
By Özge Özkaya
The use of lipid nanoparticles carrying methotrexate seems to be safe and feasible in women with deep infiltrating endometriosis, according to a new study published in the scientific journal Archives of Gynecology and Obstetrics. The approach could, therefore, be a new…
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By Nasuhi Engin AydinReviewing all you want to know on endometriosis !
By Nasuhi Engin Aydin
Academicians from the International University of Sarajevo, Bosnia, and Lincoln Medical School, UK have written a comprehensive updated review on endometriosis covering many aspects of endometriosis and published their paper as an open-access manuscript in the journal “Pathology-Research and Practice”. …
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Exploring endometriosis symptoms and their effects on women's lives
By Eylül GÜN
Endometriosis symptoms, their severity, and the way they affect patients' lives may vary. With the aim of investigating different personal experiences and perceptions of endometriosis symptoms and the way they impact women's daily lives, Hunsche and colleagues from Switzerland and…
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By Hale Goksever CelikTreatment of superficial dyspareunia using topical estrogens in postmenopausal women with a history of endometriosis
By Hale Goksever Celik
Genitourinary syndrome of menopause is defined as a collection of symptoms and signs caused by hypoestrogenic changes to the labia majora/minora, clitoris, vestibule/introitus, vagina, urethra, and bladder that occur in menopausal patients. Sexual dysfunction and superficial dyspareunia can be experienced…
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A Starch-Based Gel Barrier Reduces Pain and Improves Fertility After Endometriosis Surgery
By Özge Özkaya
The development of pain was reduced in women with endometriosis who underwent surgery for deep infiltrating endometriosis (DIE) resection and the "gel barrier 4DryField® PH" was used during the operation, according to results from a randomized controlled trial. Moreover, fertility was improved. "4DryField® PH"…
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Pain Scoring System for Deep Endometriosis
By Selma Oransay
The numeric pain scale is commonly used to interpret pain score values. According to the National Comprehensive Cancer Network guidelines, pain scores of 4-7 points indicate moderate, and 8-10 points indicate severe pain. Patients with a local pain score of…
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The effect of dienogest vs ethynyl estradiol/dienogest on quality of life in women with endometriosis
By Hale Goksever Celik
Women with endometriosis suffer from dysmenorrhea, dyspareunia, and chronic pelvic pain that diminishes the quality of their life. Both physical and mental components of quality of life have been affected by endometriosis-associated symptoms. There are several medical and surgical treatment…
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Which surgery for deep endometriosis? Laparoscopic shaving or rectal resection?
By Selma Oransay
This keynote lecture entitled "Deep endometriosis: The place of laparoscopic shaving" was presented by Dr. Jacques Donnez, the director of the infertility research unit at the Catholic University of Louvain, Brussels, Belgium, at the Annual International Medical Conference of the Endometriosis Foundation…
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Is there any advantage of addition of hysterectomy on deep endometriotic pelvic pain or on the quality of life?
By Selma Oransay
The addition of hysterectomy and salpingo-oophorectomy to the endometriosis excision surgery provided greater benefits when compared to excision surgery alone, according to the results of a comparison study that was recently published in the journal named "Facts Views and Visions in Obstetrics…
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Laparoscopic resection of bladder endometriosis
By Selma Oransay
When we talk about deep-infiltrating endometriosis, one of the most commonly affected organs in the urinary tract is the bladder, with a prevalence of 80%. Bladder endometriosis can be defined as the existence of the endometrial glands and stroma inside…
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Comparison of two surgical approaches for endometriosis.
By Selma Oransay
Endometriosis is one of the causes of infertility in women. But the pathophysiology of infertility caused by endometriosis is not yet clear. Hormonal disorders, abnormal peritoneal function, distorted pelvic anatomy, and multiple cesarean deliveries are among the accused. Dr. Li…
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By Bahar YukselWeighting (side)effects when dealing with endometriosis-associated pain.
By Bahar Yuksel
The treatment options for endometriosis-related pain are so many. And the guidelines leave the selection to the clinicians, which causes obscurity between preferences. In the study by Christine Poulos et al, the authors analyzed the response of clinicians on the…
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Younger Women With Endometriosis Feel More Pain
By Özge Özkaya
Younger women with endometriosis feel more period pain (dysmenorrhea) and pain during intercourse (dyspareunia) compared to older women with the disease, found a new study published in the Journal of Pediatric and Adolescent Gynecology. Acknowledging this fact can make sure…
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Pelvic pain characteristics in young girls with endometriosis.
By Selma Oransay
The occurrence of severe and frequent pelvic pain in young women is a piece of evidence that endometriosis begins and develops at an early age. Two-thirds of women with endometriosis who were diagnosed in their adulthood reported the onset of…
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Endometriosis Prediction by "Machine Learning"
By Selma Oransay
To develop a predictive model for endometriosis and to re-assess the contribution of known risk factors, Blass et al. from the Hebrew University of Jerusalem, Jerusalem, Israel used the data of the UK biobank by machine learning-based models. They compared and…
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What are the most common symptoms of endometriosis and how are they related to age?
By Eylül GÜN
Even though the incidence of endometriosis is relatively high and numerous studies are being conducted to elucidate its pathogenesis, it is still a highly underdiagnosed and undertreated disease. The symptoms of the disease are well-known; however, the correlation between the…
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Prevalence of endometriosis and adenomyosis by transvaginal ultrasound.
By Selma Oransay
Women who present dyspareunia, dysmenorrhea, dysuria, dyschezia, chronic abdominal, and pelvic pain, and infertility would benefit from the early investigation. If the correct diagnosis of endometriosis and/or adenomyosis can be made in advance, early treatment will improve the quality of…
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Algorithm for pain management in endometriosis
By Selma Oransay
One of the debilitating symptoms of endometriosis is pain. Mostly due to delayed diagnosis and the high recurrence rate, even after the surgical and hormonal therapy pain control may not be sufficient causing the patient to suffer for decades. Endometriosis-associated…
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Pain During Intercourse, What Does it Feel Like?
By Özge Özkaya
The presentation, severity, and impact of painful intercourse caused by endometriosis differ between patients, found a new study published in The Journal of Sexual Medicine. According to the authors of the study, these findings are important because they can help…
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Pain During Sex in Women With Endometriosis
By Özge Özkaya
Pain during intercourse or dyspareunia due to endometriosis manifests itself in multiple forms such as deep, introital, and/or positional. Pain can also occur at orgasm and during and/or after intercourse. These are the findings of a systemic literature review published…
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Sexual Function in Women With Endometriosis
By Özge Özkaya
The sexual function of women diagnosed with endometriosis is impaired confirmed a new study by Spanish researchers published in the Journal of Clinical Medicine. According to the study, the strongest predictive factors for poor sexual function are deep disease, depression,…
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Impact of adenomyosis on sexual life
By Selma Oransay
Considering the similar etiopathogenesis and pain symptoms between adenomyosis and deep infiltrating endometriosis, Alcalde et al. from the Department of Gynecology, University of Barcelona, Spain, aimed to call attention to the presence of potential sexual dysfunction not only in patients with deep…
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A gentle touch on nerves affects dyspareunia
By Bahar Yuksel
Endometriosis is a common disorder among women. Previous studies reported endometriosis-related deterioration of the quality of life. Deep dyspareunia is a common symptom of endometriosis and young patients face dyspareunia twice as much. Surgical treatments are alternative to medical therapies in cases…
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High-dose progestin intake and sexual functions in endometriosis patients
By Selma Oransay
Dr. Oppenheimer et al. from the Department of Reproductive Medicine and Fertility Preservation of Antoine Beclere University Hospital, Clamart, France, recently published this bi-center observational prospective study in "Acta Obstetrica et Gynecologica Scandinavica". The study was designed to put forth…
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Endometriosis and the sexual relations of the couples
By Selma Oransay
From the viewpoint of endometriotic women, the pain during the penetration is not the only complaint. They also have growing depression and anxiety leading to difficulties with their social and sexual relationship, work, and study. The emotional impact of sub-infertility,…
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By Ellen TumimbangCA125 do not correlate with pain and its severity among adolescents
By Ellen Tumimbang
Cancer antigen 125 (CA125) is a high molecular weight glycoprotein expressed in tissue derived from the coelomic and Mullerian epithelia including the uterus endometrium. Previous studies reported that CA125 is the most studied endometriosis marker. Women with endometriosis experienced different…
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By Irem OnurDyspareunia and Endometriosis
By Irem Onur
Women experience severe pain during intercourse related to endometriosis and this has a significant negative impact on the lives of women. This is according to an American study published in the "Journal of Pain Research". The study included 638 endometriosis…
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Sexual Quality of Life in Women With Endometriosis
By Özge Özkaya
Painful intercourse, more severe period pain, worse health-related quality of life, and unemployment are all associated with worse sexual quality of life in women with endometriosis. This is according to a Dutch study published in the scientific journal Sexual Medicine.…
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Pain and Quality of Life Following Surgical Treatment for Endometriosis
By Ellen Tumimbang
Currently, laparoscopy is the preferred approach as a surgical treatment of endometriosis. Many studies have shown the effectiveness of laparoscopic surgery to reduce the painful symptoms and improve the quality of life for patients with endometriosis in the short term…
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The effect of endometriosis on the quality of life
By Hale Goksever Celik
Endometriosis, the disease defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity, can be diagnosed in the reproductive-aged women with an incidence of 7-15%. However, endometriosis is observed in women with chronic pelvic pain syndrome…
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A hope for postoperative symptomatic endometriosis therapy
By Irem Onur
A new chapter in the treatment of symptomatic endometriosis patients may begin since new medical approaches including oral GnRH antagonists, selective progesterone receptor modulators, aromatase inhibitors, and peritoneal immune response modulators are being actively evaluated. To date, there was only…
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By Nadire DuruCase-control study to develop a questionnaire for early diagnosis of endometriosis
By Nadire Duru
Endometriosis, which affects 5–10% of women of reproductive age, is a chronic gynecological disease characterized by the presence of endometrial glands and stroma outside the uterus, associated with several discomforts such as pelvic pain, menstrual disorders, and infertility. Ultrasound evaluation…
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The Relationship Between Dyspareunia and Infertility in Endometriosis
By Selma Oransay
Wahl et al. from the Center of Pelvic Pain and Endometriosis British Columbia Women's Hospital, Vancouver, Canada studied with endometriotic patients suffering from dyspareunia who were referred to their center and built a cross-sectional study to investigate the relations between…
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Surgery and the endometriosis associated-pain: A systematic review
By Selma Oransay
The surgical approach for pelvic pain-related to endometriosis depends on the stage and the type of the endometriotic lesion and ranging from ablation and the excision of the lesions to radical surgery as hysterectomy with removal of ovaries and presacral…
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Patients preferences for the treatment of endometriosis-associated pain
By Hale Goksever Celik
Endometriosis is defined as the location of endometrial stroma and glands outside the uterine cavity. The most common presenting complaints are mainly dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility, most of which relate to the menstrual period. Those women affected…
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By Yu YuClinical trial for the use of oral lactobacillus on endometriosis pain severity
By Yu Yu
The standard treatment of endometriosis consists of surgery and hormonal based treatment. There is evidence for the efficacy of these types of treatment, although their side effects remain a critical consideration for women. Based on molecular studies, changes in the…
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By Deniz KocasSexual distress, metacognitive beliefs, and endometriosis
By Deniz Kocas
In this study, researchers from the University of Bergamo in Italy investigated the link between sexual distress and psychological and cognitive factors in women with endometriosis. Compared to the general female population, women with endometriosis have a nine-fold increased risk…
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The pain and its severity in deeply infiltrating endometriosis patients
By Selma Oransay
Liang et al. from the Department of Obstetrics and Gynecology of the First Affiliated Hospital of Sun Yat-sen University, China, recently published an interesting paper in the Journal of Pain Research, a prospective study to reveal the relationship between neurogenesis and other potential…
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Endometriosis, Pain and Quality of Life
By Deniz Kocas
Although studies show that pain in endometriosis is associated with decreased health-related quality of life (HRQoL), details as to which pain symptoms contribute to such a decline have not been explored. For the first time in this study, researchers from…
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How to improve the current ASRM classification of endometriosis?
By Selma Oransay
In this article which recently published in Best Practice&Research Clinical Obst&Gyn. from the University of Sao Paulo, Brazil, Andres et al. penned a review of the classification of endometriosis in chronological order, and discussed the limitations of existing classification systems to…
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By Murat OsmanHealth-related quality of life in women with Endometriosis and Rheumatoid Arthritis
By Murat Osman
Endometriosis is a chronic inflammatory disease that is defined by the presence of ectopic endometrial tissue outside of the uterus. Unfortunately, endometriosis continues to be a leading cause of chronic pelvic pain and long-term morbidity in women of reproductive age.…
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By Kasthuri NairDifficulties Associated with Diagnosing Ascites and Encapsulating Peritonitis in Endometriosis
By Kasthuri Nair
De Magalhães et al. recently published a paper titled “Ascites and Encapsulating Peritonitis in Endometriosis: a Systematic Review with a Case Report” in Revista Brasileira de Ginecologia e Obstetrícia. The team from the Universidade Federal do Ceará and the Universidade…
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Deep Infiltrating Endometriosis Impairs Sexual Function
By Kasthuri Nair
Lima et al., a group of scientists from Hospital do Servidor Público Estadual in Brazil, recently published an article entitled “Female Sexual Function in Women with Suspected Deep Infiltrating Endometriosis” in Revista Brasileira De Ginecologia E Obstetricia. The paper analyzed…
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Thoracic Endometriosis Syndrome : A case report describing endometriosis involvement of the lung
By Murat Osman
Leonardo-Pinto and authors from the Universidade Estadual de Campinas, Brazil, have recently published a case report titled, "Hemoptysis and Endometriosis: An Unusual Association - Case Report and Review of the Literature" in the Journal, Revista Brasileira De Ginecologia E Obstetricia describing a…
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Severe Dyspareunia is Related with "Cul-de-sac" and "Uterosacral Ligament" Endometriosis
By Murat Osman
Endometriosis and especially deep infiltrating endometriosis has been associated with an increased risk of severe dyspareunia. Studies reporting the anatomical sites associated with deep dyspareunia and the severity of pain, and the risk factors of these anatomic sites are incongruent;…
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Reduced vascularization in ovarian endometriomas associated with less pain
By Yu Yu
Angiogenesis, i.e., the development of new blood vessels is believed to play an important role in endometriosis pathogenesis and symptoms. Endometriosis is associated and requires neovascularization to proliferate, invade surrounding normal structure in order to establish an endometriotic lesion. Ovarian…
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Combo Therapy of Micronized palmitoylethanolamide/trans-polydatin for Endometriosis Pain
By Kasthuri Nair
Endometriosis is a painful illness and many researchers in the field work to offer women with the disease some form of respite from the suffering. Indraccolo, Indraccolo, and Mignini are three such researchers and they recently published a paper titled…
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Sexual Pain in Endometriosis
By Yu Yu
Pelvic pain during sexual intercourse (deep dyspareunia) is a major concern for women with endometriosis. As many as half of women with endometriosis experience deep dyspareunia and has been shown to have a detrimental impact on quality of life. The…
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Dienogest for endometriosis pain in clinical practice
By Yu Yu
Dienogest is a synthetic progestogen that has been marketed as a medical treatment for endometriosis. Previous randomized controlled clinical trials have shown that it is effective in women with endometriosis at different stages of the disease. Given its recent introduction,…
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The Benefits of Primary Surgery
By Kasthuri Nair
Ahmad, Hussin, and Ahmad recently conducted a cohort study, and they published the results within an article titled “An evaluation of the quality of life in women with endometriosis who underwent primary surgery: a 6-month follow-up in Sabah Women &…
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The Unresolved Link Between Sexual Dysfunction and Endometriosis
By Kasthuri Nair
Barbara et al. recently published a systematic review of literature in Reproductive Sciences titled “What Is Known and Unknown About the Association Between Endometriosis and Sexual Functioning” that delves into the effects that endometriosis has on female sexual dysfunction. Endometriosis…
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Does laparoscopic excision or laparoscopic ablation offer the best long-term pain relief from endometriosis?
By Murat Osman
This systematic and meta-analysis of several studies aimed to compile data regarding the reduction of dysmenorrhea (menstrual pain), dyschezia (difficult defecation), dyspareunia (painful sexual intercourse), chronic pelvic pain and Endometriosis Health Profile (EHP-30) score 2-12 months after treatment. Visual analog scale (VAS)…
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