Evaluating chronic pain through art
Chronic non-cancer pain, affecting up to 31% of the global population, is a complex condition defined by persistent or recurring pain lasting over three months. Despite advancements in understanding chronic pain as a multifaceted interaction of biological, psychological, and social…
Key Points Lay SummaryEndometriosis-associated symptoms have a negative impact on the quality of life in women
Women with endometriosis experience restrictions in their daily activities due to pelvic pain, resulting in abstinence from work or school and discontinuation of their social activities. Evaluation and management of endometriosis-associated symptoms is important to prevent these significant consequences. However, successful…
Key Points Lay SummaryA concerning link between endometriosis and cardiovascular disease.
Endometriosis is a disease characterized by endometrial-like tissues outside the uterus, which causes inflammation, scarring, and adhesion formation. The pathologic process of forming those adhesions releases proinflammatory molecules, cytokines, and growth factors that may have systemic effects. Recent research, for…
Key Points Lay SummaryEndometriosis and the risk to have mental disorders
The most common clinical findings of endometriosis patients are pelvic pain and fertility problems, resulting in impairment of quality of life. These women are also affected regarding psychological health due to disease-associated symptoms. Dr. Wang et al., from Taiwan, published…
Key Points Lay SummaryThe urgent need for research and compassionate care in endometriosis
Endometriosis, a common yet little-known inflammatory disorder, has significant patient and public health impacts due to underinvestment in its research and care. Delayed diagnosis and inadequate care persist due to reliance on surgical methods and limited advancements in medical therapies.…
Key Points Lay SummaryCould H1-antihistamines be beneficial in endometriosis management ?
K. B. Manthra, PhD, a postdoctoral researcher from the University of Minnesota has written a “clinical opinion” in a recent issue of the periodical American Journal of Obstetrics and Gynecology, Global Reports. Endometriosis is currently regarded as a chronic inflammatory…
Key Points Lay SummaryNew developments in endometriosis from a molecular and cellular standpoint
Researchers are making significant progress in endometriosis regarding molecular and cellular research, with collaborative efforts by clinicians, scientists, surgeons, and biostatisticians. Laganà et al. from Italy wrote an editorial regarding the recent special issue called "Molecular and Cellular Advances in Endometriosis Research…
Key Points Lay SummaryWomen With Endometriosis Willing to Participate in Research
Women with endometriosis are open to participating in research, according to a new Australian study published in the journal "Medicina (Kaunas)". This way, they said, “they felt aligned with their needs, with a significant focus on diagnostic tools and symptom…
Key Points Lay SummaryTime has come to learn more about endometriosis and take action!
It has been a long time since endometriosis was defined. Extensive population studies have shown that around 10% of women suffer from this condition. Depending on its severity, it alters the various functions of the body and causes the patients…
Key Points Lay SummaryAre the studies based on the nationwide databases more accurate?
One of the most common localizations of endometriosis is the ovaries, and therefore, ovarian endometriomas are among the most surgically treated endometriotic lesions. Dr. Roman from Denmark has recently written an editorial about the surgical interventions on ovarian endometrioma and…
Key Points Lay SummaryA quick insight into the latest research on endometriosis diagnosis and management
Endometriosis research has been expanding with many new studies ranging from new techniques and markers in diagnosis to updates in clinical management and treatment of the disease. The journal Frontiers in Surgery recently brought together articles that reflect important and…
Key Points Lay SummaryMachine learning tools to predict endometriosis
The current gold standard diagnostic method for endometriosis is the surgical diagnosis and yet no approaches have been found to replace it. In the study conducted by Sofiane Bendifallah et al, the authors aimed to use machine learning algorithms to…
Key Points Lay SummaryInternational definition and standardization for endometriosis
There is huge heterogeneity in classifications, subtypes, diagnostic and therapeutic interventions of endometriosis in published literature. The lack of a uniform and widely accepted terminology of the disease rose the necessity to argue and reach a common consensus with organizations,…
Key Points Lay SummaryEtiopathogenesis of Endometriosis and Links with Endometrial Cancer
Professor Terzic and colleagues from the Medical School of Nazarbayev University, Kazakhstan published their review on the molecular aspects of endometriosis and endometrial cancer in “International Journal of Molecular Sciences”. The etiopathogenesis of endometriosis has remained controversial, with recent studies…
Key Points Lay SummaryRetinol-binding protein in endometriosis pathogenesis
Dr. Jae Chul Lee and associates from the Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, have published the recent results of their research on endometriosis regarding the role of retinol-binding protein4…
Key Points Lay SummaryA Call for Pan-Canadian Collaboration for the Care and Quality of Life of Endometriosis Patients
Wahl KJ et al., from Canada, drew attention to the lack of health care for endometriosis patients who are estimated to be 1 million in number in Canada in their recent brief communication report. The delay in the diagnosis, the…
Key Points Lay SummaryA miniaturized version of endometrium: organoids for endometriosis research
Organoids are a miniaturized version of a tissue that is produced in culture through three dimensions techniques in order to better mimic the tissues of origin. These cultures are supposed to better replicate the complexity of a biological organ/disease. Endometrial…
Key Points Lay SummaryPriorities and Unmet Needs of Endometriosis Management
Endometriosis is a systemic, chronic disease that is a significant contributor to morbidity in young women. Although endometriosis has gained increasing attention in the medical field, scientific progress for an effective and definitive treatment modality is progressing slowly. The Society…
Key Points Lay SummaryEFA Medical Conference 2017: EFA Research Grants Presentation by Dr. Serin Seckin
Dr. Serin Seckin, a Resident Physician at Mount Sinai Health System, gave a presentation during the 2017 Medical Conference titled “EFA Research Grants.” This presentation delineated and went into some detail about the research grants worth over $400,000 that were…
Key Points Lay SummaryTFF3 May Be Involved in Endometriosis Research Suggests
Levels of a protein called TFF3 are significantly increased in the peritoneal cavity (the abdominal space) of women with endometriosis, found a study published in the scientific journal Reproductive Sciences. This increase was in line with levels of other known…
Lay SummaryCan a cure be developed for endometriosis?
The Lancet correspondence highlights that regardless of the importance of endometriosis; its full socioeconomic impact is underestimated and endometriosis research is considerably underfunded. The Endometriosis Priority Setting Partnership (PSP) which includes women with endometriosis, their supporters, health-care practitioners, endometriosis researchers, and representatives from…
Key Points Lay Summary